ID S9YRX6_CAMFR Unreviewed; 917 AA.
AC S9YRX6;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=HMG box domain-containing protein {ECO:0000259|PROSITE:PS50118};
GN ORFNames=CB1_000301021 {ECO:0000313|EMBL:EPY86715.1};
OS Camelus ferus (Wild bactrian camel) (Camelus bactrianus ferus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus.
OX NCBI_TaxID=419612 {ECO:0000313|EMBL:EPY86715.1, ECO:0000313|Proteomes:UP000030684};
RN [1] {ECO:0000313|EMBL:EPY86715.1, ECO:0000313|Proteomes:UP000030684}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=bactrian camel {ECO:0000313|Proteomes:UP000030684};
RX PubMed=23149746;
RG Bactrian Camels Genome Sequencing and Analysis Consortium;
RA Jirimutu, Wang Z., Ding G., Chen G., Sun Y., Sun Z., Zhang H., Wang L.,
RA Hasi S., Zhang Y., Li J., Shi Y., Xu Z., He C., Yu S., Li S., Zhang W.,
RA Batmunkh M., Ts B., Narenbatu, Unierhu, Bat-Ireedui S., Gao H.,
RA Baysgalan B., Li Q., Jia Z., Turigenbayila, Subudenggerile, Narenmanduhu,
RA Wang Z., Wang J., Pan L., Chen Y., Ganerdene Y., Dabxilt, Erdemt, Altansha,
RA Altansukh, Liu T., Cao M., Aruuntsever, Bayart, Hosblig, He F., Zha-ti A.,
RA Zheng G., Qiu F., Sun Z., Zhao L., Zhao W., Liu B., Li C., Chen Y.,
RA Tang X., Guo C., Liu W., Ming L., Temuulen, Cui A., Li Y., Gao J., Li J.,
RA Wurentaodi, Niu S., Sun T., Zhai Z., Zhang M., Chen C., Baldan T.,
RA Bayaer T., Li Y., Meng H.;
RT "Genome sequences of wild and domestic bactrian camels.";
RL Nat. Commun. 3:1202-1202(2012).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TCF/LEF family.
CC {ECO:0000256|ARBA:ARBA00006569}.
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DR EMBL; KB016593; EPY86715.1; -; Genomic_DNA.
DR AlphaFoldDB; S9YRX6; -.
DR Proteomes; UP000030684; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:InterPro.
DR CDD; cd21996; HMG-box_TCF7-like; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR024940; TCF/LEF.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR10373:SF33; TRANSCRIPTION FACTOR 7; 1.
DR PANTHER; PTHR10373; TRANSCRIPTION FACTOR 7 FAMILY MEMBER; 1.
DR Pfam; PF00505; HMG_box; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Reference proteome {ECO:0000313|Proteomes:UP000030684};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687}.
FT DOMAIN 696..764
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 696..764
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 621..693
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 759..791
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 654..669
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 767..787
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 917 AA; 106351 MW; D4BBF4AD6938D972 CRC64;
MQDVQEPLSG HSLQVHHRKT SFLLQREDWQ ELKLDEVSRG KNMEGDSQMC RNCKRSVASA
HLALHEAHCL LFLVLCPECK EAVPQEKMDE HCRGGHQQVG CAMCQQSLPK HSLEVHEATE
CQERPVECKF CELAVRLSKV ELHEHHCGRR TKLCPGCGQL FMLHVLAKHR DVCRGEQARL
QEGEMLVVSF VKRKTSEKFQ LEPEKKRKWN QMMYSADLWR YRTITFSGRP SRVHASEFES
ALWYVKKFGH YLEHLEIKFL NPYNAVLTKK FQVTMRGLLS CLGKSNNRLK SLSIQHLELD
RLVWRNSIRS SFIKSLSFFL KKMGKHLDYL NLKGARLTVE QGCHVLNSLS YLRSKSMVSE
LNIEDYFSHH LAVYSSLQFH KTMATFRSLV SLTLNYNCIS DELLENLCEN NAGTLWTMNV
KCHVHDPHSQ VIWGMSWAKL ARHATSLKVN FFFERVMKHE RLARILLQEI PVRSISLRSC
YFSDPDWSMR PTLTDLLPTF RHTLQKLTFE FNNNHESLDE ELHLLILSCR KLFYFKIWAF
LDVKFVERIL KSQEEGQCAL RTLKVRIYTN RCETNEEDRT LREIYRKYRK LIDSELNYFV
IAYPMIGRDV WEADRRLPVT PSLTGKNSQR PAPPHPTPQL DDLDVPDELV AFQNEGEEQD
HKSRDSATGP RARPGRAQPE AQAESKALKE AKKPTIKKPL NAFMLYMKEM RAKVTAECTL
KETAAISQIL GRRWHALSQE EWARYYELAR KERQPHMQLN PGWLGRDNYG KKKRWSREKH
QESNRDPGSP KHAVLALASV SRRIVLLAAP GPRPPRTRPH TSCCPTFPQN CLLALPSQRL
HYQKNPKHAI TTDGLLPNLE AQPEEAVFLR AVKLYNSGGF RSSTEDRERA LAEYLAIFAR
CLAGCEGAHE QADFKDF
//
