ID S9ZDX7_9RHOO Unreviewed; 630 AA.
AC S9ZDX7;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Acetyl-CoA synthetase {ECO:0000313|EMBL:EPZ15480.1};
DE EC=6.2.1.17 {ECO:0000313|EMBL:EPZ15480.1};
GN Name=prpE {ECO:0000313|EMBL:EPZ15480.1};
GN ORFNames=M622_15825 {ECO:0000313|EMBL:EPZ15480.1};
OS Thauera terpenica 58Eu.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Zoogloeaceae;
OC Thauera.
OX NCBI_TaxID=1348657 {ECO:0000313|EMBL:EPZ15480.1, ECO:0000313|Proteomes:UP000015455};
RN [1] {ECO:0000313|EMBL:EPZ15480.1, ECO:0000313|Proteomes:UP000015455}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=58Eu {ECO:0000313|EMBL:EPZ15480.1,
RC ECO:0000313|Proteomes:UP000015455};
RA Liu B., Frostegard A.H., Shapleigh J.P.;
RT "Draft genome sequence of Thauera terpenica.";
RL Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPZ15480.1}.
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DR EMBL; ATJV01000056; EPZ15480.1; -; Genomic_DNA.
DR RefSeq; WP_021249458.1; NZ_ATJV01000056.1.
DR AlphaFoldDB; S9ZDX7; -.
DR STRING; 1348657.M622_15825; -.
DR PATRIC; fig|1348657.5.peg.2036; -.
DR eggNOG; COG0365; Bacteria.
DR OrthoDB; 9766486at2; -.
DR Proteomes; UP000015455; Unassembled WGS sequence.
DR GO; GO:0050218; F:propionate-CoA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0019629; P:propionate catabolic process, 2-methylcitrate cycle; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR012694; Propion_PrpE.
DR NCBIfam; TIGR02316; propion_prpE; 1.
DR PANTHER; PTHR43347; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43347:SF3; ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:EPZ15480.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000015455}.
FT DOMAIN 4..58
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 60..440
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 511..594
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 630 AA; 69395 MW; AE68304064F46273 CRC64;
MTDYQQFYRR SIDDRDGFWA EQAQLVHWNK PIEQVCDYSQ PPFVKWFKGG ETNLCYNAVD
RHAAQRPDDR ALVYISTETN EEKVYSFAEL QREVERMAAI YQELGVRRGD RVLIYMPMIA
EAAFAMLACA RIGAIHSVVF GGFAAGSLAT RIDDAKPVLM VSSDAGMRNG KPVPYKHLVD
EACTLAEFPP ARVLIVNRGL DKGFSRVAGR DVDYAELRAK HMDAQVPVEW MESSAPSYIL
YTSGTTGKPK GVQRDTGGYC VALAASMKHI FAGNPGETMF ATSDIGWVVG HSYIVYGPLI
GGMATIMYEG TPLRPDAGIW WQIVEKYQVS VMFSAPTAVR VLKKQDPAFL KKYDLSSLRQ
LFLAGEPLDE TSHQWIMEEL GIPVIDNYWQ TETGWPMLSI CRGVDGSPIK LGSPAFPVYG
YDLRIFREDG SECDANEKGI VGIMPPLPPG CLSTVWGQDD RFVSTYFSLF TDPVVYSSSD
WGIKDDKGYH SILGRMDDVI NVAGHRLGTR EIEEAVQAHP AIAEVAVVGV ADALKGQMPM
AFAVVKDASV VDTAEKRAAL EKEVMKKVDA SLGAIARPAR VLFIGGLPKT RSGKMLRRSI
QALAEGRDAG DLTTIDDPST LDQIKAALKG
//
