ID SAR1A_BRACM Reviewed; 193 AA.
AC O04266;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1997, sequence version 1.
DT 24-JAN-2024, entry version 99.
DE RecName: Full=GTP-binding protein SAR1A;
GN Name=SAR1A;
OS Brassica campestris (Field mustard).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=3711;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=9154984; DOI=10.1023/a:1005731209124;
RA Kim W.Y., Cheong N.E., Je D.Y., Kim M.G., Lim C.O., Bahk J.D., Cho M.J.,
RA Lee S.Y.;
RT "The presence of a Sar1 gene family in Brassica campestris that suppresses
RT a yeast vesicular transport mutation Sec12-1.";
RL Plant Mol. Biol. 33:1025-1035(1997).
CC -!- FUNCTION: Involved in transport from the endoplasmic reticulum to the
CC Golgi apparatus. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000250}. Golgi
CC apparatus {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in most tissues.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. SAR1 family.
CC {ECO:0000305}.
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DR EMBL; U55035; AAC49716.1; -; mRNA.
DR PIR; T52094; T52094.
DR AlphaFoldDB; O04266; -.
DR SMR; O04266; -.
DR Proteomes; UP000011750; Unplaced.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
DR CDD; cd00879; Sar1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR006689; Small_GTPase_ARF/SAR.
DR InterPro; IPR006687; Small_GTPase_SAR1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR45684:SF30; GTP-BINDING PROTEIN SAR1A; 1.
DR PANTHER; PTHR45684; RE74312P; 1.
DR Pfam; PF00025; Arf; 1.
DR PRINTS; PR00328; SAR1GTPBP.
DR SMART; SM00177; ARF; 1.
DR SMART; SM00178; SAR; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51422; SAR1; 1.
PE 2: Evidence at transcript level;
KW Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; GTP-binding;
KW Nucleotide-binding; Protein transport; Reference proteome; Transport.
FT CHAIN 1..193
FT /note="GTP-binding protein SAR1A"
FT /id="PRO_0000206267"
FT BINDING 27..34
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT BINDING 70..73
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT BINDING 129..132
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
SQ SEQUENCE 193 AA; 21967 MW; 454398FF39721FF6 CRC64;
MFVIDWFYGV LASLGLWQKE AKILFLGLDN AGKTTLLHML KDERLVQHQP TQHPTSEELS
IGKIKFKAFD LGGHQIARRV WKDYYAKVDA VVYLVDAYDK ERFAESKKEL DALLSDESLA
TVPFLILGNK IDIPYAASED ELRYHLGLSN FTTGKGKVDL VGSNVRPLEV FMCSIVRKMG
YGEGFKWLSQ YIK
//
