ID SNU71_CANGA Reviewed; 613 AA.
AC Q6FTU2;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2004, sequence version 1.
DT 24-JAN-2024, entry version 80.
DE RecName: Full=U1 small nuclear ribonucleoprotein component SNU71;
GN Name=SNU71; OrderedLocusNames=CAGL0F08811g;
OS Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 /
OS NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Nakaseomyces.
OX NCBI_TaxID=284593;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- FUNCTION: Component of the U1 snRNP particle, which recognizes and
CC binds the 5'-splice site of pre-mRNA. Together with other non-snRNP
CC factors, U1 snRNP forms the spliceosomal commitment complex, that
CC targets pre-mRNA to the splicing pathway (By similarity).
CC {ECO:0000250}.
CC -!- SUBUNIT: Component of the U1 snRNP particle, a subcomplex of the
CC spliceosome. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SNU71 family. {ECO:0000305}.
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DR EMBL; CR380952; CAG59276.1; -; Genomic_DNA.
DR RefSeq; XP_446352.1; XM_446352.1.
DR AlphaFoldDB; Q6FTU2; -.
DR SMR; Q6FTU2; -.
DR STRING; 284593.Q6FTU2; -.
DR EnsemblFungi; CAGL0F08811g-T; CAGL0F08811g-T-p1; CAGL0F08811g.
DR GeneID; 2887569; -.
DR KEGG; cgr:CAGL0F08811g; -.
DR CGD; CAL0131178; CAGL0F08811g.
DR VEuPathDB; FungiDB:CAGL0F08811g; -.
DR eggNOG; KOG2253; Eukaryota.
DR HOGENOM; CLU_031562_0_0_1; -.
DR InParanoid; Q6FTU2; -.
DR OMA; YDHHRSF; -.
DR Proteomes; UP000002428; Chromosome F.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1390.10; PWI domain; 1.
DR InterPro; IPR002483; PWI_dom.
DR Pfam; PF01480; PWI; 1.
PE 3: Inferred from homology;
KW Coiled coil; Cytoplasm; mRNA processing; mRNA splicing; Nucleus;
KW Reference proteome; Ribonucleoprotein; RNA-binding; Spliceosome.
FT CHAIN 1..613
FT /note="U1 small nuclear ribonucleoprotein component SNU71"
FT /id="PRO_0000333456"
FT REGION 333..384
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 293..332
FT /evidence="ECO:0000255"
FT COILED 367..443
FT /evidence="ECO:0000255"
FT COMPBIAS 357..376
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 613 AA; 71750 MW; 498F6486BAD3A3FD CRC64;
MLEDALVPDD KLIYVSPENL YYCYANDTID QDDKWTSIQP QQGYIPILSA NLRAYKIELL
KKLRFSGQNN VSPSIKKEKK NLEPNKKITT KPTESTGSKK YLIPEQFIPD SLEKQLRTLT
VILKDALYLG KNNRFIKENE VVSDDTRLLI LDEFLKLIIP NYIDSLANWT LVDLNKGTDD
ESLLYLRFNE SGTQSMISFY KKHSKMAKYM EIHYDTNTEK YINDNFKDDG DEDNVEAEQS
HSVGEILKSM ETAFEKARSQ VGTFKGDIND DQDDKINYKI DYNTLLDIPS DSLEQLTKEI
LNFRTKVIDI EKQKQLRQQY EDNERRQKHM TQLFEKLRKG TKSNDSNRNM DIESTDTIND
SDSEEDDDEE DEDDLAIEKR KEEKRKEEEA RKYRALLKDY ETTIEPHLHL LSQQYKQNLE
YEKELAANRE ANVKDLLRQA NDIYYDKDRS FKDREEQEDK LDREKYGDII IEDIVIDDDR
KGQKKLLEKD KKVKKAGEPA IKINLAFKKA MDNSIQDKRD KAEDIEPVSQ PIEARSTNRY
AALKEKRVVD ELVKELLGVY EDDVVAYVFE ILEKPEMSDE KKQSELVTEM EDLFDKEGAV
QFAEQVFKAL DEA
//
