ID T0AWP7_9RHOO Unreviewed; 142 AA.
AC T0AWP7;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=L-2,4-diaminobutyric acid acetyltransferase {ECO:0000256|ARBA:ARBA00017935, ECO:0000256|RuleBase:RU365045};
DE Short=DABA acetyltransferase {ECO:0000256|RuleBase:RU365045};
DE EC=2.3.1.178 {ECO:0000256|ARBA:ARBA00012355, ECO:0000256|RuleBase:RU365045};
GN Name=ectA {ECO:0000256|RuleBase:RU365045};
GN ORFNames=M622_17195 {ECO:0000313|EMBL:EPZ14973.1};
OS Thauera terpenica 58Eu.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Zoogloeaceae;
OC Thauera.
OX NCBI_TaxID=1348657 {ECO:0000313|EMBL:EPZ14973.1, ECO:0000313|Proteomes:UP000015455};
RN [1] {ECO:0000313|EMBL:EPZ14973.1, ECO:0000313|Proteomes:UP000015455}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=58Eu {ECO:0000313|EMBL:EPZ14973.1,
RC ECO:0000313|Proteomes:UP000015455};
RA Liu B., Frostegard A.H., Shapleigh J.P.;
RT "Draft genome sequence of Thauera terpenica.";
RL Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to
CC gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl
CC coenzyme A. {ECO:0000256|RuleBase:RU365045}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + L-2,4-diaminobutanoate = (2S)-4-acetamido-2-
CC aminobutanoate + CoA + H(+); Xref=Rhea:RHEA:16901, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57288, ChEBI:CHEBI:58761,
CC ChEBI:CHEBI:58929; EC=2.3.1.178;
CC Evidence={ECO:0000256|ARBA:ARBA00000400,
CC ECO:0000256|RuleBase:RU365045};
CC -!- PATHWAY: Amine and polyamine biosynthesis; ectoine biosynthesis; L-
CC ectoine from L-aspartate 4-semialdehyde: step 2/3.
CC {ECO:0000256|ARBA:ARBA00004978, ECO:0000256|RuleBase:RU365045}.
CC -!- SIMILARITY: Belongs to the acetyltransferase family. EctA subfamily.
CC {ECO:0000256|ARBA:ARBA00010712, ECO:0000256|RuleBase:RU365045}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPZ14973.1}.
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DR EMBL; ATJV01000065; EPZ14973.1; -; Genomic_DNA.
DR AlphaFoldDB; T0AWP7; -.
DR STRING; 1348657.M622_17195; -.
DR PATRIC; fig|1348657.5.peg.2524; -.
DR eggNOG; COG0456; Bacteria.
DR UniPathway; UPA00067; UER00122.
DR Proteomes; UP000015455; Unassembled WGS sequence.
DR GO; GO:0033816; F:diaminobutyrate acetyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0019491; P:ectoine biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd04301; NAT_SF; 1.
DR Gene3D; 3.40.630.30; -; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR012772; Ectoine_EctA.
DR InterPro; IPR000182; GNAT_dom.
DR NCBIfam; TIGR02406; ectoine_EctA; 1.
DR Pfam; PF00583; Acetyltransf_1; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR PROSITE; PS51186; GNAT; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU365045};
KW Reference proteome {ECO:0000313|Proteomes:UP000015455};
KW Transferase {ECO:0000256|RuleBase:RU365045}.
FT DOMAIN 1..132
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
SQ SEQUENCE 142 AA; 15404 MW; 67E9821760624D1E CRC64;
MVKATGELEP NTAYCYLLLA TDFADTCLVA EAAGQIVGAV IGYRPPREPD AAFVWQVGVL
PDYRGLGLGL RMLTAWRDLP ANRNCRWVTA TVADDNPASQ SLFQRLAHSA GVECTVNPHF
TADLFPVAHP AEPLHRIGPF SL
//
