ID T0FS26_9LEPT Unreviewed; 543 AA.
AC T0FS26;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=DNA-binding helix-turn-helix protein {ECO:0000313|EMBL:EQA72360.1};
GN ORFNames=LEP1GSC059_3738 {ECO:0000313|EMBL:EQA72360.1};
OS Leptospira noguchii serovar Panama str. CZ214.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=1001595 {ECO:0000313|EMBL:EQA72360.1, ECO:0000313|Proteomes:UP000015442};
RN [1] {ECO:0000313|EMBL:EQA72360.1, ECO:0000313|Proteomes:UP000015442}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CZ214 {ECO:0000313|EMBL:EQA72360.1,
RC ECO:0000313|Proteomes:UP000015442};
RA Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA Sanka R., DePew J., Purushe J., Hartskeerl R.A., Ahmed A.,
RA van der Linden H., Goris M.G.A., Vinetz J.M., Sutton G.G., Nierman W.C.,
RA Fouts D.E.;
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQA72360.1}.
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DR EMBL; AKWY02000018; EQA72360.1; -; Genomic_DNA.
DR RefSeq; WP_017214994.1; NZ_AKWY02000018.1.
DR AlphaFoldDB; T0FS26; -.
DR GeneID; 23201427; -.
DR Proteomes; UP000015442; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 2.60.40.2380; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR011623; 7TMR_DISM_rcpt_extracell_dom1.
DR InterPro; IPR011622; 7TMR_DISM_rcpt_extracell_dom2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR PANTHER; PTHR43280; ARAC-FAMILY TRANSCRIPTIONAL REGULATOR; 1.
DR PANTHER; PTHR43280:SF2; BIFUNCTIONAL TRANSCRIPTIONAL ACTIVATOR_DNA REPAIR ENZYME ADAA; 1.
DR Pfam; PF07695; 7TMR-DISM_7TM; 1.
DR Pfam; PF07696; 7TMR-DISMED2; 1.
DR Pfam; PF12833; HTH_18; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000313|EMBL:EQA72360.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 194..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 219..239
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 425..531
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
SQ SEQUENCE 543 AA; 63509 MW; 5E6DD3E5F143C678 CRC64;
MYKTPTSNFR IFVLAFGIFI SNFPVFAHPE AVLLTQETSS KNISSLIEYR YRGQQFAGCS
PDHIDGLEDL EWHQIPTEVL RVKRTPFGNW LRFSVKNSES TIQSRILLLG WLNVPDTQLC
FFDKNGKFVS AKSGYSNRIE DQKILTNLPH FRIDIEPNEN RIFYLFVLSN EDINYRIQIM
GLEEFELRKR LRSIISYSII GIVAIAIFYS LFGYYRFRNF TFVSFLLYII SVLITFYFLH
GRTFAEIAGN TNNLFRHSYF LFLGISYVFL FLYLFSVDKT NQKKVYRSVF FWIAGALGVL
YFLIPLLHSW YDHRILLLVV TVGLSSFYFI RVHYQFLGPN SPIGFLYTAS WAVFLVLDIY
KTIFHFDFYP FNYFSVFGVV LFLPFHSILV SFSLNEFFNR KKSQKLEDKD SIQTRKSTTS
SLNVIEIVHS VKNLLEKKKV FLQKSLKEEN VAKELGLSLH QLSEIINVEF GNNFPSLINQ
YRVEEAKKLL LDHPDKTTAE IGSSAGFSSK SAFYMEFKKF TGTNPNAYRR KELKNESTFR
KNF
//
