ID T0FXX8_9LEPT Unreviewed; 705 AA.
AC T0FXX8;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=7TM diverse intracellular signaling {ECO:0000313|EMBL:EQA78852.1};
GN ORFNames=LEP1GSC193_1786 {ECO:0000313|EMBL:EQA78852.1};
OS Leptospira alstonii serovar Pingchang str. 80-412.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=1218564 {ECO:0000313|EMBL:EQA78852.1, ECO:0000313|Proteomes:UP000015445};
RN [1] {ECO:0000313|EMBL:EQA78852.1, ECO:0000313|Proteomes:UP000015445}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=80-412 {ECO:0000313|EMBL:EQA78852.1,
RC ECO:0000313|Proteomes:UP000015445};
RA Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA Sanka R., DePew J., Purushe J., Galloway R.L., Vinetz J.M., Sutton G.G.,
RA Nierman W.C., Fouts D.E.;
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQA78852.1}.
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DR EMBL; AOHD02000062; EQA78852.1; -; Genomic_DNA.
DR RefSeq; WP_020772470.1; NZ_AOHD02000062.1.
DR AlphaFoldDB; T0FXX8; -.
DR STRING; 28452.A0128_20815; -.
DR Proteomes; UP000015445; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 2.60.40.2380; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR011623; 7TMR_DISM_rcpt_extracell_dom1.
DR InterPro; IPR011622; 7TMR_DISM_rcpt_extracell_dom2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR Pfam; PF07695; 7TMR-DISM_7TM; 1.
DR Pfam; PF07696; 7TMR-DISMED2; 1.
DR Pfam; PF13581; HATPase_c_2; 1.
DR Pfam; PF00989; PAS; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..705
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004575424"
FT TRANSMEM 191..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 253..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 416..468
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
SQ SEQUENCE 705 AA; 81015 MW; 8B3AD3A0BD83F6DD CRC64;
MIWKLRKAFV FLILVFSGAL HSEPPRSAEF EPNAVMEGWD LQSYLTYYED KSGKLSFPEI
QKVFQSGKSI PLFNNSLGYS DATVWVRVPV SNSERGTKNW VLLFSYTMID SLRFYSVRNG
ALPLSVSGDE LPFATRLAEN RNFPFQLSEP PLSKNDYYLR IESKNSIIVP LSAYSRTEFL
EHTAKEYTAL GFYYGTMCVM FVYNLFLLIT TRDISYLYYS IFIFFDILFQ MTLNGLSFQF
LWPNHPEWGN VSLPFFIFSA FLAACLFGKS FLESSKMTPI TDKFYYPIMA ICGFGCIGSL
TFFSHTFSVI SSIVVLLIVL TLLLINSLQC VWKGHRPSRF FLTAWSVFIL GSFLYAMNAF
GIFSDNFFTQ WGLQIGSAIE VAFLSLGLAD RIKQLSLTLE MQAISLNLLK QRHEQSAVQY
KNLYEGEEDF LFDLDSNGTI TGSNKSISPF LGFKPQDVIG KNFLEFMYNT GGLEDAFKKL
YVMERMEELY STRKPVYFRA DFVQKYLKEP KELQVRLQIL EHESGRDILG RAFEPDQDLM
GRYLDEERIV FSMNNYLQNA ELLSQRLTFN LVRFTDPTAA LSIRTSLREM LVNAIEHGNL
NISEEDKARC LKNGNYFQFI LARQNDPYYR DKKILVEYFL SGQKVGYRIT DEGKGFNHAR
TVRNALSKTD ENAALRTGGI AFALSAFDVV KFNSTGNRVT LVKYF
//
