ID T0G9X7_9LEPT Unreviewed; 320 AA.
AC T0G9X7;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=3-beta hydroxysteroid dehydrogenase/isomerase family protein {ECO:0000313|EMBL:EQA43589.1};
GN ORFNames=LEP1GSC050_1658 {ECO:0000313|EMBL:EQA43589.1};
OS Leptospira broomii serovar Hurstbridge str. 5399.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=1049789 {ECO:0000313|EMBL:EQA43589.1, ECO:0000313|Proteomes:UP000015454};
RN [1] {ECO:0000313|EMBL:EQA43589.1, ECO:0000313|Proteomes:UP000015454}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=5399 {ECO:0000313|EMBL:EQA43589.1,
RC ECO:0000313|Proteomes:UP000015454};
RA Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA Sanka R., DePew J., Purushe J., Hartskeerl R.A., Ahmed A.,
RA van der Linden H., Goris M.G.A., Vinetz J.M., Sutton G.G., Nierman W.C.,
RA Fouts D.E.;
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQA43589.1}.
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DR EMBL; AHMO02000011; EQA43589.1; -; Genomic_DNA.
DR RefSeq; WP_010570062.1; NZ_AHMO02000011.1.
DR AlphaFoldDB; T0G9X7; -.
DR STRING; 1049789.LEP1GSC050_1658; -.
DR OrthoDB; 9811743at2; -.
DR Proteomes; UP000015454; Unassembled WGS sequence.
DR GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR48079; PROTEIN YEEZ; 1.
DR PANTHER; PTHR48079:SF6; PROTEIN YEEZ; 1.
DR Pfam; PF01073; 3Beta_HSD; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Isomerase {ECO:0000313|EMBL:EQA43589.1}.
FT DOMAIN 5..248
FT /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF01073"
SQ SEQUENCE 320 AA; 35108 MW; DC264734B871F742 CRC64;
MRIFITGASG FVGGAIAKRL KENHSVLALS RSAESDAILK KAGLEVFRGK LGAIPSDALR
EIDIVVHCAA FVGPWGNRKD FWEANVDGTS QLLEAAKAAG VKRFIHMGTE AALFHGQDMI
KIDETYPYPN QTPYLYSETK AEAEKRVLAA NSEKFKTISL RPRLVWGPGD TSVLPVLKKM
VSEGKFLWIN GGKARTSTTY IQNLAYAAEL ALTQGIGGQS YFITDDEDQT FRSFLLSMMK
TQGIDLPNGS VPSFLARSLA FIVESVWNLF GIQSEPPLMR FATDIMAKEC TIKIDKAKRE
LGYAPKISVA QGLIAMKEFG
//
