ID   T0H7G0_9SPHN            Unreviewed;       596 AA.
AC   T0H7G0;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=Dihydroxy-acid dehydratase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=L288_08915 {ECO:0000313|EMBL:EQB08038.1};
OS   Sphingobium quisquiliarum P25.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingobium.
OX   NCBI_TaxID=1329909 {ECO:0000313|EMBL:EQB08038.1, ECO:0000313|Proteomes:UP000015525};
RN   [1] {ECO:0000313|EMBL:EQB08038.1, ECO:0000313|Proteomes:UP000015525}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=P25 {ECO:0000313|EMBL:EQB08038.1,
RC   ECO:0000313|Proteomes:UP000015525};
RX   PubMed=24029763;
RA   Kumar Singh A., Sangwan N., Sharma A., Gupta V., Khurana J.P., Lal R.;
RT   "Draft Genome Sequence of Sphingobium quisquiliarum Strain P25T, a Novel
RT   Hexachlorocyclohexane (HCH)-Degrading Bacterium Isolated from an HCH
RT   Dumpsite.";
RL   Genome Announc. 1:e00717-13(2013).
CC   -!- SIMILARITY: Belongs to the IlvD/Edd family.
CC       {ECO:0000256|ARBA:ARBA00006486}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EQB08038.1}.
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DR   EMBL; ATHO01000072; EQB08038.1; -; Genomic_DNA.
DR   AlphaFoldDB; T0H7G0; -.
DR   PATRIC; fig|1329909.3.peg.1724; -.
DR   Proteomes; UP000015525; Unassembled WGS sequence.
DR   GO; GO:0016836; F:hydro-lyase activity; IEA:InterPro.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019752; P:carboxylic acid metabolic process; IEA:UniProt.
DR   GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR   Gene3D; 3.50.30.80; IlvD/EDD C-terminal domain-like; 1.
DR   InterPro; IPR042096; Dihydro-acid_dehy_C.
DR   InterPro; IPR000581; DiOHA_6PGluconate_deHydtase.
DR   InterPro; IPR020558; DiOHA_6PGluconate_deHydtase_CS.
DR   InterPro; IPR037237; IlvD/EDD_N.
DR   PANTHER; PTHR43183:SF1; HYPOTHETICAL DIHYDROXY-ACID DEHYDRATASE (EUROFUNG)-RELATED; 1.
DR   PANTHER; PTHR43183; HYPOTHETICAL DIHYDROXYACID DEHYDRATASE (EUROFUNG)-RELATED; 1.
DR   Pfam; PF00920; ILVD_EDD; 1.
DR   SUPFAM; SSF143975; IlvD/EDD N-terminal domain-like; 1.
DR   SUPFAM; SSF52016; LeuD/IlvD-like; 1.
DR   PROSITE; PS00886; ILVD_EDD_1; 1.
PE   3: Inferred from homology;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
SQ   SEQUENCE   596 AA;  64525 MW;  C2D20F3B2157C545 CRC64;
     MPCAAAWIGR IAFQNRNLFM SDAPKSPRRS TAWFGGSDRA AFLHRSWMKG QGHPDDMFDG
     RPIIGICNTW SDLTPCNAHF RALAERIKRG VYEAGGFPVE FPVSSLGEPT MRPTTMLFRN
     LVSMDVEEAI RAHPIDGVVL MVGCDKTTPA LMMGAASCDL PTLVLSGGPM LNGKFRGHDI
     GSGTDVFRFM DALKTGDMLL AEVSEAESGM TRSIGHCMTM GTASSMASMV EAIGMGLPDN
     ATIPAADTRR WRLAQLVGRR IVGMVEEDLT FSKVVDRRSI ENAIRVNAAL GGSTNAVLHL
     LALAGRLEID LTLDDWDRLG RDVPTIVNLK PSGDYLMEDF YYAGGIPGVI RRLGEAGLLH
     RDAATVNGRT IWENNSEAPI YNEDVIRPFE RSLMASGGVV VLRGNIAENG AIMKPSAATP
     RLSQHRGRAI VFDSIEEYRA RIDDPELDID ADSIMVLRNC GPTGYPGMPE VGNMGLPAKL
     LRQGVKDMVR ISDARMSGTA YGTVILHCAP EAAVGGGLAL VQEGDIIEVD VANRRLHLDV
     APDVLEQRRA AWTPPAPGMT SGYQYMHASH VLQADRGADL DFLVGRRGAA VPREST
//