ID T0HLY5_9SPHN Unreviewed; 936 AA.
AC T0HLY5;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN ORFNames=L284_14650 {ECO:0000313|EMBL:EQB13198.1};
OS Novosphingobium lindaniclasticum LE124.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Novosphingobium.
OX NCBI_TaxID=1096930 {ECO:0000313|EMBL:EQB13198.1, ECO:0000313|Proteomes:UP000015527};
RN [1] {ECO:0000313|EMBL:EQB13198.1, ECO:0000313|Proteomes:UP000015527}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LE124 {ECO:0000313|EMBL:EQB13198.1,
RC ECO:0000313|Proteomes:UP000015527};
RX PubMed=24029761;
RA Saxena A., Nayyar N., Sangwan N., Kumari R., Khurana J.P., Lal R.;
RT "Genome Sequence of Novosphingobium lindaniclasticum LE124T, Isolated from
RT a Hexachlorocyclohexane Dumpsite.";
RL Genome Announc. 1:e00715-13(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQB13198.1}.
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DR EMBL; ATHL01000090; EQB13198.1; -; Genomic_DNA.
DR RefSeq; WP_021234754.1; NZ_ATHL01000090.1.
DR AlphaFoldDB; T0HLY5; -.
DR PATRIC; fig|1096930.3.peg.2917; -.
DR eggNOG; COG5001; Bacteria.
DR OrthoDB; 9814202at2; -.
DR Proteomes; UP000015527; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-UniRule.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR005330; MHYT_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF03707; MHYT; 2.
DR Pfam; PF12860; PAS_7; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50924; MHYT; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|PROSITE-ProRule:PRU00244};
KW Reference proteome {ECO:0000313|Proteomes:UP000015527};
KW Transmembrane {ECO:0000256|PROSITE-ProRule:PRU00244};
KW Transmembrane helix {ECO:0000256|PROSITE-ProRule:PRU00244}.
FT TRANSMEM 16..35
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 56..78
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 84..103
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 110..130
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 142..162
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 174..195
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT DOMAIN 12..199
FT /note="MHYT"
FT /evidence="ECO:0000259|PROSITE:PS50924"
FT DOMAIN 247..320
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 322..374
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 536..668
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 677..927
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT REGION 913..936
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 936 AA; 102558 MW; E0D5EEB6309629A8 CRC64;
MFDIYLCIRD GHDLKFVLLA ALICLLSSLT ALALLRQAAD STGSARRRWW CMAGASAGFG
IWATHFVAML GFAPGIVIGF ESGLTLTSLI IPVVALSLSF GLLTESKGRF VLIGASALAA
LGIAAMHYTG MMAMEVPGVL RWKTGFLAAS VIIAFLPLYP AFTLALEDRR LRGLLAATAL
LSASVVGLHF TGMTGMTIIP TRLHAIEQLI SPREMAGAVA GVSFLLVALS AISLVVSRRT
AAAVALSERN FSFLVRGISD CAIYMLDLEG RVRNWNAGAQ RLKGYAEDEV IGLHVSSFYT
PEDREAALDR VALEAARSQG RYHGEGWRVR KDGSRFWAHV TMEPMLDDLG QPIAFAKITR
DMTRFKEALD RTAEANRQRD AALGHMHQGL CLFGADEKLV LSNIRYLEMY GLAPDALRPG
MSLSEVIRLS SLTRFAPHLI ADRVRVAERA IRDNLATDAH SPILAEYPDG KVVSIATRPM
PGGGWVSTFD DVTRQRESEA QIAHMAMHDG LTGLPNRTRF NLWIDEMLEQ ASRHGKRLGV
AAIDLDRFKE INDTYGHSWG DVVLAELARR LGSALGEEEI AARLGGDEFG LAKLFDSDEQ
LAEFLRRIEP CFTQPVAHQG QELSFGASLG IAAYPHDGID REALLNNADL AMYRAKAQIG
ERICYYEPGM DEIARARRQL ANDLRLAVER DELVLLYQPQ CQLRSGQLSG YEALVRWHHP
LHGLVSPAEF IPIAEESGAI LQIGEWVLAQ ACREAATWHS HHRVAVNVSP VQLVQQDLAP
MVGRVLTETG LSASRLELEI TESAIITDKV RALNNLRQLK ELGVAIAMDD FGTGYSSLDT
LHSFPFDKIK IDKSFLLESD QNEQARAIIR AVLALGSSLR IPVLAEGVET ASQFELLISE
GCEEAQGYFL GRPDRAPSLK SESPDTVPET RAEAFA
//
