ID T0TWJ7_9STRE Unreviewed; 226 AA.
AC T0TWJ7;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Aspartate-semialdehyde dehydrogenase {ECO:0000313|EMBL:EQC77735.1};
DE EC=1.2.1.11 {ECO:0000313|EMBL:EQC77735.1};
GN ORFNames=HSISM1_1315 {ECO:0000313|EMBL:EQC77735.1};
OS Streptococcus sp. HSISM1.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1316408 {ECO:0000313|EMBL:EQC77735.1};
RN [1] {ECO:0000313|EMBL:EQC77735.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HSISM1 {ECO:0000313|EMBL:EQC77735.1};
RA Van den Bogert B., Boekhorst J., Herrmann R., Smid E.J., Zoetendal E.G.,
RA Kleerebezem M.;
RT "Comparative Genomics Analysis of Streptococcus Isolates from the Human
RT Small Intestine Reveals their Adaptation to a Highly Dynamic Ecosystem.";
RL PLoS ONE 8:E83418-E83418(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQC77735.1}.
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DR EMBL; ASKI01000037; EQC77735.1; -; Genomic_DNA.
DR AlphaFoldDB; T0TWJ7; -.
DR PATRIC; fig|1316408.3.peg.865; -.
DR eggNOG; COG0136; Bacteria.
DR HOGENOM; CLU_049966_3_1_9; -.
DR Proteomes; UP000015933; Chromosome.
DR GO; GO:0004073; F:aspartate-semialdehyde dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0008652; P:amino acid biosynthetic process; IEA:InterPro.
DR InterPro; IPR012280; Semialdhyde_DH_dimer_dom.
DR PANTHER; PTHR46278:SF2; ASPARTATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR46278; DEHYDROGENASE, PUTATIVE-RELATED; 1.
DR Pfam; PF02774; Semialdhyde_dhC; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:EQC77735.1}.
FT DOMAIN 5..196
FT /note="Semialdehyde dehydrogenase dimerisation"
FT /evidence="ECO:0000259|Pfam:PF02774"
SQ SEQUENCE 226 AA; 25066 MW; F355539BD38C27DE CRC64;
MMVALEPVRQ KWGLDRIIVS TYQAVSGAGM GAILETQREL KEVLNDGVNP RDVKAEILPC
GGDKKHYPIA FNALPQIDVF TENDYTYEEM KMTNETKKIM EDDSIAVSAT CVRIPVLSAH
SESVYIETKE VAPIDEVKAA IAEFPGAVLE DDVAHQIYPQ AVNAVGSRDT FVGRIRKDLD
AEKGIHMWVV SDNLLKGAAW NSVQIAETLH ERGLVRPTAE LKFELK
//
