ID T0UUH8_LACLC Unreviewed; 1569 AA.
AC T0UUH8;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Helicase {ECO:0000313|EMBL:EQC87101.1};
GN ORFNames=LLT7_13830 {ECO:0000313|EMBL:EQC87101.1};
OS Lactococcus cremoris subsp. cremoris TIFN7.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Lactococcus; Lactococcus cremoris subsp. cremoris.
OX NCBI_TaxID=1234877 {ECO:0000313|EMBL:EQC87101.1, ECO:0000313|Proteomes:UP000015724};
RN [1] {ECO:0000313|EMBL:EQC87101.1, ECO:0000313|Proteomes:UP000015724}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TIFN7 {ECO:0000313|EMBL:EQC87101.1,
RC ECO:0000313|Proteomes:UP000015724};
RX PubMed=23823494; DOI=10.1038/ismej.2013.108;
RA Erkus O., de Jager V.C., Spus M., van Alen-Boerrigter I.J.,
RA van Rijswijck I.M., Hazelwood L., Janssen P.W., van Hijum S.A.,
RA Kleerebezem M., Smid E.J.;
RT "Multifactorial diversity sustains microbial community stability.";
RL ISME J. 7:2126-2136(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQC87101.1}.
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DR EMBL; ATBA01000170; EQC87101.1; -; Genomic_DNA.
DR PATRIC; fig|1234877.3.peg.1401; -.
DR Proteomes; UP000015724; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR CDD; cd17926; DEXHc_RE; 1.
DR CDD; cd22333; LlaBIII_nuclease-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR003356; DNA_methylase_A-5.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR039442; Mrr-like_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011335; Restrct_endonuc-II-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR041635; Type_ISP_LLaBIII_C.
DR PANTHER; PTHR47396:SF1; ATP-DEPENDENT HELICASE IRC3-RELATED; 1.
DR PANTHER; PTHR47396; TYPE I RESTRICTION ENZYME ECOKI R PROTEIN; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF13156; Mrr_cat_2; 1.
DR Pfam; PF02384; N6_Mtase; 1.
DR Pfam; PF04851; ResIII; 1.
DR Pfam; PF18135; Type_ISP_C; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52980; Restriction endonuclease-like; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:EQC87101.1};
KW Helicase {ECO:0000313|EMBL:EQC87101.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000313|EMBL:EQC87101.1}.
FT DOMAIN 181..386
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 477..647
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 1569 AA; 178836 MW; 943C085C7999B8B7 CRC64;
MTKQTFNDLI NQINTVSKDV QRERGTLFEK LTLAYLKNEP TYKALYQNVW LLSEVPESYG
IPKKDTGVDL VAEQKNGDLV AIQAKFYTNK VGKSEINSFV AELGKSYYQR GLIVSTMDDW
NSNARETIDQ NEKGIEIIGL SDLRNSQIDW SQFNFERPEN VVVKKPKKLR DYQQTAKENA
LAHFKENDRG QLIMAPGTGK TFTSLKISEA LSKDKNGPFK VLYLVPSIQL LTQTLRGWNN
DTELTITSMA VTSDRDASRG TDGTEDIKAS DIGYPATTSS KKILQNWHDF ESLPKQTDML
VVFSTYQSIE VIGEAQKEGF PEFDFIISDE AHRTTGAHEA AKEASAFSKV HSNNNVKGLK
RMYQTATPKI YGESAKKNAK DKSILLSSMD DESKYGEVFF RMGFGQAVSR DILTDYKVMV
LAVDEAAIQK DMQRTLADPE NGLNIDDVGR IVGIWNGMMR RNGYKNPIKN SPYDGAPLER
AIAFTRTIEE SKKVSSQFEE VVNEYISEAI EDESIHLSMR HADGQMNALQ KGEVLDWLAN
PNKPADEARI VSNVRFLTEG IDIPTLDAVI FLSPKKSQVD IVQAVGRIMR KAEGKDYGYI
ILPIVIPTGE KPETILDNNK NYETVWQVIN ALRSVDERFE AMIDKLNMAK PKQLKVIGVG
SSPDQVNDQD KTTENTPVQT ELEFEWDKFE GAIFGKIVQK VGDRKYLENW SKDVAKIAER
QINWIKNKLS DKKDPISLEF KKFVSSLQHN INDSIDEKQA AEMLSQHLIT KPIFEALFSE
YSFVNQNPVS QAMESIVSEL EKAGFAKEQE NLEPLYESVR MRAEGIEKAE DKQKIIVTLY
DKFFKTAFKA TTERLGIVFT PIEVVDFIVH SVDDVLKKHF GKSLASKDVH ILDPFTGTGT
FIVRTLTYLK EQMDAGEISL ADITRKFMKE LHANEIVLLS YYIAAINIES TFDEINGDEE
GYVPFEGIVL TDTFESTETE DTLDDDYFGT NDERLKRQQK VPITVIMGNP PYSAKQKNED
GNQIRTTYEK LDASLQNSWV ETSTATNKNN LFDSYIRAMR WSSDRISDNG VIGFITNNSF
IDGNAMDGMR QSLLEEFSDI YVLNLKGGIR GKTKDQSALE GGNIFDIMTG VTIIMLIKKS
DYTVEGRIHY LDIGNNLDKY QKLEKLKNWK SLNGATSEFQ NIIPNEKGDW INQRNSNFDE
LISLGNKKGS DSLFIDYTGG LKTGRDNWSW NFSKEQVELS MKSSIDYYNQ YLGDTNIYKE
DVPDISWTRS LKQRFERRET QSWQGERMYL GMYRPFTKKH VYYAQAWIDR QYQMTKVLPS
STSSNLMISL SNKTGGKQFS TLIVDVLPDV NLFTGGSQNL PKYLYRNNDT GNLFDNSEKY
SAIRHEVLNK LPNLSEEDAM YYVYGLFHSI QYGKVYYEDL AKSFPKIPNV KHKEKYIKIG
KELADLHLNY ENQPICEGID VQISELNYRV KKMKHPKKGV LDTIIYNESI TIKNIPEKAY
EYVVNGRPAI EWIINQYQVK TDKKSGITDD PNEFSDDPKY ILNLLLSVIT VSMRTLELID
ELPEFEIQE
//
