ID T0UXE3_9STRE Unreviewed; 201 AA.
AC T0UXE3;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE SubName: Full=Response regulator of the competence regulon ComE {ECO:0000313|EMBL:EQC74349.1};
GN ORFNames=HSISM1_568 {ECO:0000313|EMBL:EQC74349.1};
OS Streptococcus sp. HSISM1.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1316408 {ECO:0000313|EMBL:EQC74349.1};
RN [1] {ECO:0000313|EMBL:EQC74349.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HSISM1 {ECO:0000313|EMBL:EQC74349.1};
RA Van den Bogert B., Boekhorst J., Herrmann R., Smid E.J., Zoetendal E.G.,
RA Kleerebezem M.;
RT "Comparative Genomics Analysis of Streptococcus Isolates from the Human
RT Small Intestine Reveals their Adaptation to a Highly Dynamic Ecosystem.";
RL PLoS ONE 8:E83418-E83418(2013).
CC -!- FUNCTION: Required for high-level post-exponential phase expression of
CC a series of secreted proteins. {ECO:0000256|ARBA:ARBA00037164}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQC74349.1}.
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DR EMBL; ASKI01000101; EQC74349.1; -; Genomic_DNA.
DR AlphaFoldDB; T0UXE3; -.
DR PATRIC; fig|1316408.3.peg.27; -.
DR eggNOG; COG3279; Bacteria.
DR HOGENOM; CLU_000445_14_6_9; -.
DR Proteomes; UP000015933; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
DR CDD; cd17533; REC_LytTR_AgrA-like; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 2.40.50.1020; LytTr DNA-binding domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR046947; LytR-like.
DR InterPro; IPR007492; LytTR_DNA-bd_dom.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR37299:SF3; STAGE 0 SPORULATION PROTEIN A HOMOLOG; 1.
DR PANTHER; PTHR37299; TRANSCRIPTIONAL REGULATOR-RELATED; 1.
DR Pfam; PF04397; LytTR; 1.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00850; LytTR; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR PROSITE; PS50930; HTH_LYTTR; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169}.
FT DOMAIN 1..84
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 100..201
FT /note="HTH LytTR-type"
FT /evidence="ECO:0000259|PROSITE:PS50930"
FT MOD_RES 17
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 201 AA; 23146 MW; B6EF3FDD46CBC371 CRC64;
MLDAITERGA HHLFFLDIEI KGEEKKGLEI AKEIRKKDPH ATIVFVTTHS EFMPITFQYK
VAALDFIDKT LGEEEFKERI SSAIDYTLEQ AGTTIAQDAF TFESAMARVQ VPFNKILYVE
TSPTIHKVIL HTQEERLEFY ASIADIEKAD PRLYRCHRSF VVNPQNITKI DKEAKKAFFE
NGDNCLISRT KYRGLLEALK K
//
