ID T0VA61_9STRE Unreviewed; 246 AA.
AC T0VA61;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Transcriptional regulator, MerR family {ECO:0000313|EMBL:EQC76358.1};
GN ORFNames=HSISM1_1977 {ECO:0000313|EMBL:EQC76358.1};
OS Streptococcus sp. HSISM1.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1316408 {ECO:0000313|EMBL:EQC76358.1};
RN [1] {ECO:0000313|EMBL:EQC76358.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HSISM1 {ECO:0000313|EMBL:EQC76358.1};
RA Van den Bogert B., Boekhorst J., Herrmann R., Smid E.J., Zoetendal E.G.,
RA Kleerebezem M.;
RT "Comparative Genomics Analysis of Streptococcus Isolates from the Human
RT Small Intestine Reveals their Adaptation to a Highly Dynamic Ecosystem.";
RL PLoS ONE 8:E83418-E83418(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQC76358.1}.
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DR EMBL; ASKI01000069; EQC76358.1; -; Genomic_DNA.
DR AlphaFoldDB; T0VA61; -.
DR PATRIC; fig|1316408.3.peg.1528; -.
DR eggNOG; COG0789; Bacteria.
DR HOGENOM; CLU_060077_0_6_9; -.
DR Proteomes; UP000015933; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd01106; HTH_TipAL-Mta; 1.
DR Gene3D; 1.10.1660.10; -; 1.
DR Gene3D; 1.10.490.50; Antibiotic binding domain of TipA-like multidrug resistance regulators; 1.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR InterPro; IPR047057; MerR_fam.
DR InterPro; IPR036244; TipA-like_antibiotic-bd.
DR InterPro; IPR012925; TipAS_dom.
DR PANTHER; PTHR30204:SF90; HTH-TYPE TRANSCRIPTIONAL ACTIVATOR TIPA; 1.
DR PANTHER; PTHR30204; REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR; 1.
DR Pfam; PF13411; MerR_1; 1.
DR Pfam; PF07739; TipAS; 1.
DR PRINTS; PR00040; HTHMERR.
DR SMART; SM00422; HTH_MERR; 1.
DR SUPFAM; SSF89082; Antibiotic binding domain of TipA-like multidrug resistance regulators; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..69
FT /note="HTH merR-type"
FT /evidence="ECO:0000259|PROSITE:PS50937"
SQ SEQUENCE 246 AA; 28291 MW; 7848AD6CBDB4E0BC CRC64;
MYHIKKAAEL SGVSIKTLHH YDKIGLLVPV KSENGYRTYS QEDLERLQVI LYYKYLGFSL
DQIAELLAEE KSNLLPHLTK QLTYLTQERE RLDTLISTLQ KTIQEQKGER QMTIEEKFTG
FSYQDTQKYH QEAVDKYGQE VMNQALERQK GREYEATRAF NQVFQTLSQN LKDGLPVSAN
ENQDQAAKLL DAIRTYGFDC SIEVFGHIGK GYVYNPEFKG NIDKFGAGTA QYTSDVIASY
VENQPK
//
