ID   T1AN65_9ZZZZ            Unreviewed;       456 AA.
AC   T1AN65;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=PmbA protein {ECO:0000313|EMBL:EQD57933.1};
GN   ORFNames=B2A_04605 {ECO:0000313|EMBL:EQD57933.1};
OS   mine drainage metagenome.
OC   unclassified sequences; metagenomes; ecological metagenomes.
OX   NCBI_TaxID=410659 {ECO:0000313|EMBL:EQD57933.1};
RN   [1] {ECO:0000313|EMBL:EQD57933.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Mendez C., Richter M., Ferrer M., Sanchez J.;
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EQD57933.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=24430486; DOI=10.1038/ismej.2013.242;
RA   Mendez-Garcia C., Mesa V., Sprenger R.R., Richter M., Diez M.S., Solano J.,
RA   Bargiela R., Golyshina O.V., Manteca A., Ramos J.L., Gallego J.R.,
RA   Llorente I., Martins Dos Santos V.A., Jensen O.N., Pelaez A.I., Sanchez J.,
RA   Ferrer M.;
RT   "Microbial stratification in low pH oxic and suboxic macroscopic growths
RT   along an acid mine drainage.";
RL   ISME J. 8:1259-1274(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EQD57933.1}.
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DR   EMBL; AUZZ01003103; EQD57933.1; -; Genomic_DNA.
DR   AlphaFoldDB; T1AN65; -.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR   InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR   InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR   InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR   InterPro; IPR047657; PmbA.
DR   InterPro; IPR035068; TldD/PmbA_N.
DR   InterPro; IPR036059; TldD/PmbA_sf.
DR   PANTHER; PTHR43421; METALLOPROTEASE PMBA; 1.
DR   PANTHER; PTHR43421:SF1; METALLOPROTEASE PMBA; 1.
DR   Pfam; PF01523; PmbA_TldD_1st; 1.
DR   Pfam; PF19290; PmbA_TldD_2nd; 1.
DR   Pfam; PF19289; PmbA_TldD_3rd; 1.
DR   SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE   4: Predicted;
FT   DOMAIN          41..105
FT                   /note="Metalloprotease TldD/E N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01523"
FT   DOMAIN          133..239
FT                   /note="Metalloprotease TldD/E central"
FT                   /evidence="ECO:0000259|Pfam:PF19290"
FT   DOMAIN          247..454
FT                   /note="Metalloprotease TldD/E C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19289"
SQ   SEQUENCE   456 AA;  47612 MW;  0FF233055D4E44E4 CRC64;
     MPNAVIAAGD ADSSPVAELD RLAAIAADVI TRARGAGASA AEVSASVETG LNVSVRLGEV
     ETVEHTRDRG FSLTVYFGQR KGSASTADLK SESIAATLEH ACAIARYTEP DPAAGLADAA
     LMANQFPDLD LWHPWPLSVD DAVELAQRCE AAGLAVAGIG NSEGASVGSG SALEVYANSH
     GFIGREHATQ HSMSCALIAG NGEDGMQRDY WWDSARARDD LMDAAALGRR AAERTLARLG
     ARPLGTRTCK VLFTPDTARS LLGHLVGAVS GGALYRRASF LLDQLGQSLF PAHINIIERP
     RLPRGPASAA FDAEGVATHE HPLIENGVLK RYVLGSYSAR KLGLASTANA GGVRNLILEP
     GALDFAQMLD AMGTGLVVTE LMGQGVNTVT GDYSRGAAGY WVERGVIAHP VEEVTIASNL
     RAMFADIEAV GSDLDARGGL MTPSLLIREM TVAGAE
//