ID T1DLW3_CROHD Unreviewed; 553 AA.
AC T1DLW3;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE RecName: Full=Phospholipase B-like {ECO:0000256|RuleBase:RU364138};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU364138};
OS Crotalus horridus (Timber rattlesnake).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Viperidae; Crotalinae; Crotalus.
OX NCBI_TaxID=35024 {ECO:0000313|EMBL:JAA96126.1};
RN [1] {ECO:0000313|EMBL:JAA96126.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Venom gland {ECO:0000313|EMBL:JAA96126.1};
RX PubMed=23758969; DOI=10.1186/1471-2164-14-394;
RA Rokyta D.R., Wray K.P., Margres M.J.;
RT "The genesis of an exceptionally lethal venom in the timber rattlesnake
RT (Crotalus horridus) revealed through comparative venom-gland
RT transcriptomics.";
RL BMC Genomics 14:394-394(2013).
CC -!- FUNCTION: Putative phospholipase. {ECO:0000256|RuleBase:RU364138}.
CC -!- SIMILARITY: Belongs to the phospholipase B-like family.
CC {ECO:0000256|ARBA:ARBA00007835, ECO:0000256|RuleBase:RU364138}.
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DR EMBL; GAAZ01001817; JAA96126.1; -; mRNA.
DR AlphaFoldDB; T1DLW3; -.
DR GO; GO:0004620; F:phospholipase activity; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.60.60.20; -; 1.
DR Gene3D; 2.10.70.60; Phospholipase B-like, domain 1; 1.
DR Gene3D; 1.10.439.20; Phospholipase B-like, domain 2; 1.
DR InterPro; IPR007000; PLipase_B-like.
DR InterPro; IPR043040; PLipase_B-like_dom1.
DR InterPro; IPR043041; PLipase_B-like_dom2.
DR InterPro; IPR043042; PLipase_B-like_dom3.
DR PANTHER; PTHR12370:SF1; PHOSPHOLIPASE B-LIKE 1; 1.
DR PANTHER; PTHR12370; PHOSPHOLIPASE B-RELATED; 1.
DR Pfam; PF04916; Phospholip_B; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU364138};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963,
KW ECO:0000256|RuleBase:RU364138};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098,
KW ECO:0000256|RuleBase:RU364138}; Signal {ECO:0000256|ARBA:ARBA00022729}.
SQ SEQUENCE 553 AA; 64180 MW; 167046201608EF4B CRC64;
MIRFGNPSSS DKRRQRCRSW YWGGLLLLWA VAETRADIHY ATVYWLEAEK SFQIKDVLDK
NGDAYGYYND TIQSTGWGIL EIKAGYGNQP ISNEILMYAA GFLEGYLTAS HMSDHFANLF
PLMIKNVIIE QKVKDFIQKQ DEWTRQQIKN NKDDPFWRNA GYVIAQLDGL YMGNVEWAKQ
QKRTPLTYFE ISFLNAIGDL LDLILALHSE LRKSDFRSMP DVSRMYQWDM GHCSALIKVL
PGYENIYFAH SSWFTYAATL RIYKHLDFKI TDPQTKTGRA SFSSYPGFLV SLDDFYILGS
GLIMLQTTNS VFNLSLLKKI VPESLFAWER VRIANMMADS GKTWAETFEK QNSGTYNNQY
MILDTKKIKL QRSLEDGTLY IIEQVPKLVK YSDQTKVLRN GYWPSYNIPF DKEIYNMSGY
GEYVQRHGLE FSYEMAPRAK IFRRDQGKVT DMESMKFIMR YNNYKEDPYA KRNPCNTICC
RQDLDRRTPV PAGCYDSKVA DISMAAKFTA YAINGPPVEK GLPVFSWVHF NKTKHQGLPE
SYNFDFVTMK PVL
//
