ID   T1DNH0_ANOAQ            Unreviewed;       708 AA.
AC   T1DNH0;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Putative larval serum protein 2 {ECO:0000313|EMBL:JAA98705.1};
OS   Anopheles aquasalis (Malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=42839 {ECO:0000313|EMBL:JAA98705.1};
RN   [1] {ECO:0000313|EMBL:JAA98705.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Whole body {ECO:0000313|EMBL:JAA98705.1};
RG   Brazilian Malaria Network (MCT/CNPq/MS/SCTIE/DECIT/PRONEX 555648/2009-5) and Research Network on Bioactive Molecules from Arthropod Vectors (NAP-MOBIARVE;
RG   University of Sao Paulo);
RA   Marinotti O., Ribeiro J.M.C., Costa-da-Silva A.L., Silva M.C.P.,
RA   Lopes A.R., Barros M.S., Sa-Nunes A., Konjin B.B., Carvalho E., Suesdek L.,
RA   Silva-Neto M.A.C., Capurro M.L.;
RT   "Transcriptome sequencing and developmental regulation of gene expression
RT   in Anopheles aquasalis.";
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the hemocyanin family.
CC       {ECO:0000256|ARBA:ARBA00038082}.
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DR   EMBL; GAMD01002885; JAA98705.1; -; mRNA.
DR   AlphaFoldDB; T1DNH0; -.
DR   VEuPathDB; VectorBase:AAQUA_004280; -.
DR   GO; GO:0045735; F:nutrient reservoir activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR   Gene3D; 2.60.40.1520; Hemocyanin, C-terminal domain; 1.
DR   Gene3D; 1.20.1370.10; Hemocyanin, N-terminal domain; 1.
DR   InterPro; IPR008922; Di-copper_centre_dom_sf.
DR   InterPro; IPR013788; Hemocyanin/hexamerin.
DR   InterPro; IPR000896; Hemocyanin/hexamerin_mid_dom.
DR   InterPro; IPR005203; Hemocyanin_C.
DR   InterPro; IPR037020; Hemocyanin_C_sf.
DR   InterPro; IPR005204; Hemocyanin_N.
DR   InterPro; IPR036697; Hemocyanin_N_sf.
DR   InterPro; IPR014756; Ig_E-set.
DR   PANTHER; PTHR11511:SF5; FAT-BODY PROTEIN 1-RELATED; 1.
DR   PANTHER; PTHR11511; LARVAL STORAGE PROTEIN/PHENOLOXIDASE; 1.
DR   Pfam; PF03723; Hemocyanin_C; 1.
DR   Pfam; PF00372; Hemocyanin_M; 1.
DR   Pfam; PF03722; Hemocyanin_N; 1.
DR   PRINTS; PR00187; HAEMOCYANIN.
DR   SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR   SUPFAM; SSF81296; E set domains; 1.
DR   SUPFAM; SSF48050; Hemocyanin, N-terminal domain; 1.
DR   PROSITE; PS00209; HEMOCYANIN_1; 1.
PE   2: Evidence at transcript level;
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Storage protein {ECO:0000256|ARBA:ARBA00022761}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..708
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004574865"
FT   DOMAIN          34..158
FT                   /note="Hemocyanin N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03722"
FT   DOMAIN          164..432
FT                   /note="Hemocyanin/hexamerin middle"
FT                   /evidence="ECO:0000259|Pfam:PF00372"
FT   DOMAIN          441..702
FT                   /note="Hemocyanin C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03723"
SQ   SEQUENCE   708 AA;  82901 MW;  94C27C3F166E7C0C CRC64;
     MKSFALLVLG ATFAFASAAF VPSTTEVKYA EKEFLHKQED LLLLFRHLYE KDWNPQLVAY
     AKNFHFKESP ELFKHEPTSQ WATKLWQYYE HGLLPKGEVF SVYEEHHLEQ AIALFRVLYH
     AKDWETFYKV AAWARYYCNE GMFVYALTVA VTHRPDLAGF VLPAPYEISP YHFINTEVIQ
     RAQQYKMQGY YGMSKVDGVY SVVIPANYTG WYVHTNPEQK IAYFTEDIGL NSYYYYLHTD
     YPFWLGGEQF GLKKDRRGEL YLFEHQQLLA RYYLERLSND LGHIPEFSWW KPIETGYYPD
     LQYYNGHSFP VRDNHYHADH TKHHHEIRQV VSYEKRLRDA IDQGFFMLPD GKLVNLSTPE
     SVEVLGNLIQ ANPDSFGTRF FKYVAMYARI IMGAAIEPVE HYQVIPSVLE HYESALRDPV
     FYQIYKRIVH YYYQFKDHLP KYTYDELHYP GVKIDGVVVD RLQTFFDQFD LDITNAIDIE
     PEPYVAGKYD GFGEIEYKPD PVVIKARTMR LNHKPFTYKI SLTAEKAGKS VVRVFLGPKY
     DEYGTPYTLN ANRENFYELD YFVQELTVGK NVITRTSTHF NGYVKDRTTF YELYRRVMVG
     YQGGEQFPLD MTEAHCGFPN RLMLPKGKKG GMPYQLFVIV SPYHEPAVPQ YTGFDPVLSC
     GIGSGARYVD SYAFGYPLDR PIDETVFYQV PNAFFQDVVI YHKSEGDL
//