ID T1EXH3_HELRO Unreviewed; 613 AA.
AC T1EXH3;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=BACK domain-containing protein {ECO:0000259|SMART:SM00875};
GN Name=20201273 {ECO:0000313|EnsemblMetazoa:HelroP165937};
GN ORFNames=HELRODRAFT_165937 {ECO:0000313|EMBL:ESN90291.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP165937, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESN90291.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP165937}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQM01002214; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB097753; ESN90291.1; -; Genomic_DNA.
DR RefSeq; XP_009031247.1; XM_009032999.1.
DR AlphaFoldDB; T1EXH3; -.
DR STRING; 6412.T1EXH3; -.
DR EnsemblMetazoa; HelroT165937; HelroP165937; HelroG165937.
DR GeneID; 20201273; -.
DR KEGG; hro:HELRODRAFT_165937; -.
DR CTD; 20201273; -.
DR eggNOG; KOG1072; Eukaryota.
DR HOGENOM; CLU_018559_0_0_1; -.
DR InParanoid; T1EXH3; -.
DR OrthoDB; 5472491at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011498; Kelch_2.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR45632:SF3; KELCH-LIKE PROTEIN DIABLO; 1.
DR PANTHER; PTHR45632; LD33804P; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF07646; Kelch_2; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00612; Kelch; 4.
DR SUPFAM; SSF117281; Kelch motif; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000015101};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 125..226
FT /note="BACK"
FT /evidence="ECO:0000259|SMART:SM00875"
SQ SEQUENCE 613 AA; 70031 MW; ADB5FB339E0DB7BB CRC64;
MMKDVDDVES NDDSTGERIV LISKSGGRHQ IDKNVLFRTS NYFQGLVNSG MRDAHCREFT
LECLTNESLI EVMDYFSKFS TNELESLKSL NEVEAGLDGA FYLQINDMID SYIELLLKHL
NYSTCLRILD IANKYVLIDR VVDKVIKYVS KNFKKISESS KTFLSPDEMF RLVASEEINS
DSEMDVFNLI IMWISENELR KCFAKKLLNE VRYNLMTTSE KQKCSAIFHN MNLNMNYSKD
KDSNISRTVG KLFVVGSTEK KHRGKNFFNI LPVYNFVEAC KTRSNGAEPK PIKFNPSYRR
RPPLDLFRYN ACVVDNCLYL IGQLRRKWTC REILVYDPVT AVWSKGCSMH HPRRDFYLGG
LAGHLYAVSG YTTGANETPT VEKYIPSENR WYMVEPLPLA LPSLAGCVCN GSMYVSGGVD
EIFHVRNLMY QYDPSCNKWF SRAPMLTARI SHVMTSTGNK IFAVGGKITT NGLDESFDEN
LDDYAMDGEM YDVESDQWSS VLQLKLPVYG LPSITINNCL YIFDKIPTLF LFQKINLCKY
LKEEKTSNSS SSSSMQDTNA NNINVVTNEA KEQNSHCVDT DPDDDCQILR YKNPNGKTSF
DCQYLGVMIM SDI
//
