ID T1FFX5_HELRO Unreviewed; 109 AA.
AC T1FFX5;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Tyrosine-protein kinase ephrin type A/B receptor-like domain-containing protein {ECO:0000259|Pfam:PF07699};
GN Name=20207724 {ECO:0000313|EnsemblMetazoa:HelroP180447};
GN ORFNames=HELRODRAFT_180447 {ECO:0000313|EMBL:ESN94020.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP180447, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESN94020.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP180447}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AMQM01007198; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB097579; ESN94020.1; -; Genomic_DNA.
DR RefSeq; XP_009027987.1; XM_009029739.1.
DR AlphaFoldDB; T1FFX5; -.
DR EnsemblMetazoa; HelroT180447; HelroP180447; HelroG180447.
DR GeneID; 20207724; -.
DR KEGG; hro:HELRODRAFT_180447; -.
DR CTD; 20207724; -.
DR HOGENOM; CLU_2186792_0_0_1; -.
DR InParanoid; T1FFX5; -.
DR OrthoDB; 2908764at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 1.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR011641; Tyr-kin_ephrin_A/B_rcpt-like.
DR Pfam; PF07699; Ephrin_rec_like; 1.
DR SMART; SM01411; Ephrin_rec_like; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000015101};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 89..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 23..65
FT /note="Tyrosine-protein kinase ephrin type A/B receptor-
FT like"
FT /evidence="ECO:0000259|Pfam:PF07699"
SQ SEQUENCE 109 AA; 12603 MW; 7A523CA1232CD7FE CRC64;
MKSYNICIKR DFYLPTLAPC EVGYYSEDSQ SKECLPCPNN TYQDKFGSTS CKKCPQKSEA
TENSSHCFNA EEVVLKSWKL KDEQFGDELY YLLMLATCCF IILTVFAMW
//
