ID T1FGV7_HELRO Unreviewed; 742 AA.
AC T1FGV7;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=PLAT domain-containing protein {ECO:0000259|PROSITE:PS50095};
GN Name=20208056 {ECO:0000313|EnsemblMetazoa:HelroP181307};
GN ORFNames=HELRODRAFT_181307 {ECO:0000313|EMBL:ESN92438.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP181307, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESN92438.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP181307}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00152}.
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DR EMBL; AMQM01007535; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB097640; ESN92438.1; -; Genomic_DNA.
DR RefSeq; XP_009029374.1; XM_009031126.1.
DR AlphaFoldDB; T1FGV7; -.
DR STRING; 6412.T1FGV7; -.
DR EnsemblMetazoa; HelroT181307; HelroP181307; HelroG181307.
DR GeneID; 20208056; -.
DR KEGG; hro:HELRODRAFT_181307; -.
DR CTD; 20208056; -.
DR eggNOG; KOG3599; Eukaryota.
DR HOGENOM; CLU_444519_0_0_1; -.
DR InParanoid; T1FGV7; -.
DR OrthoDB; 2879961at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR CDD; cd01756; PLAT_repeat; 2.
DR Gene3D; 2.40.180.10; Catalase core domain; 1.
DR Gene3D; 2.60.60.20; PLAT/LH2 domain; 3.
DR InterPro; IPR001024; PLAT/LH2_dom.
DR InterPro; IPR036392; PLAT/LH2_dom_sf.
DR PANTHER; PTHR45901:SF6; LIPOXYGENASE HOMOLOGY DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR45901; PROTEIN CBG12474; 1.
DR Pfam; PF01477; PLAT; 3.
DR SMART; SM00308; LH2; 3.
DR SUPFAM; SSF49723; Lipase/lipooxygenase domain (PLAT/LH2 domain); 4.
DR PROSITE; PS50095; PLAT; 4.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000015101}.
FT DOMAIN 1..73
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 130..248
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 278..416
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 528..642
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT REGION 73..128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 320..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 418..527
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..117
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 334..348
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 498..520
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 742 AA; 84037 MW; F193BC6D8F61BD74 CRC64;
SQSFLDKFKF SATDVGKITK VKIGHDHIKS NTSWTLGSLR LKTTANSRLV YVFDVNKSFD
RNSGDRLIER DLTPTTILKE SPEKSTNQKL NSHDQKHNKN KKNSNSNKNN DKNDKDDDGS
DDGGDDEDEA KYIVTTTTGN KFGSGTDSKI FVQLFGKDGE RSDRILLQKS NNKNPFERGK
VDTFEVFAPL IRKIEKVKIG HDSSKLASGW FLEELKVSCQ STGDVYGFKV GRWFDEKEED
GKINYLFFTA SSKPSKDKSP EKKAKRKKAD DKDKYERVNY DIETVTGTDF GSGTDSKVFI
QLFGVKGRTS KMFLDKTVSV SDNKKDNKND NNRNNNNKKG NSNLFETGQT DHFTVSSLNI
GKIKKVRIGH DGTKLGSGWY LSRLKVTTPA NRAYLFSVGK WLDEEDSKNE IYIFPDGAKS
KNETETNNSK SRKNNGNNKK KKTAKSSSPA KTGSKNKPTK HGKIDNDGEE EEEEENDNDT
GNKHNHDHHH HHHHEDRTKD REKKSDSDDD DDDEKNKNHS SDSTTTTTTY TISVKTGNKF
GAGTDSEVYV ALHGKSRTTD RLILKKSLSK SKNPFERNSL DVFQMDAVDV GKITIGHNGT
KFGSGWFLDH VTVERSNQVF MFNVDRWLDK REDDGKIERE IDATTIEVVI WAAPYAFIFD
ALMNPRASAG EQERMNWKTN EVILKRVWLV CVKCAEERKL DLPEFCITKC GHFDCEKRSN
VANRPNDVIA NFDGRRSVSF ES
//
