ID T1FSS0_HELRO Unreviewed; 873 AA.
AC T1FSS0;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=UV radiation resistance-associated gene protein {ECO:0008006|Google:ProtNLM};
GN Name=20211867 {ECO:0000313|EnsemblMetazoa:HelroP191237};
GN ORFNames=HELRODRAFT_191237 {ECO:0000313|EMBL:ESO06903.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP191237, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESO06903.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP191237}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQM01003705; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB096275; ESO06903.1; -; Genomic_DNA.
DR RefSeq; XP_009014999.1; XM_009016751.1.
DR AlphaFoldDB; T1FSS0; -.
DR STRING; 6412.T1FSS0; -.
DR EnsemblMetazoa; HelroT191237; HelroP191237; HelroG191237.
DR GeneID; 20211867; -.
DR KEGG; hro:HELRODRAFT_191237; -.
DR CTD; 20211867; -.
DR eggNOG; KOG2896; Eukaryota.
DR HOGENOM; CLU_329088_0_0_1; -.
DR InParanoid; T1FSS0; -.
DR OrthoDB; 5481315at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0005768; C:endosome; IBA:GO_Central.
DR GO; GO:0000323; C:lytic vacuole; IBA:GO_Central.
DR GO; GO:0032991; C:protein-containing complex; IEA:UniProt.
DR GO; GO:0000149; F:SNARE binding; IBA:GO_Central.
DR GO; GO:0035493; P:SNARE complex assembly; IBA:GO_Central.
DR InterPro; IPR018791; UV_resistance/autophagy_Atg14.
DR PANTHER; PTHR15157; UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN; 1.
DR PANTHER; PTHR15157:SF5; UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN; 1.
DR Pfam; PF10186; ATG14; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000015101}.
FT REGION 70..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 211..261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 801..830
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 283..344
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 243..259
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 873 AA; 97851 MW; DA3DF062B702DCAC CRC64;
MHSQPNSDNY YFLKQRRVRH LKGIMLKNLR LKKEINSYVE LCSFSLFFTL HKDSNSTECK
NKINQIATTI SNNNNSNNNN NNKDGGDEQN EPCTNNTNTD DEHSEPYANV SYNDISYQTF
HRYHYINNIC HSNNNDGDNN NKCDDINICN NNNNNNSHNN ISDSIVLVTT LEANFKNLVP
ISLHHTHVYN ANAIVLDFDD GLFCLAPTDH DHPKHHSSND QLQQQQHTST NIHPHHHPHH
HHHHKDDDDD GDGKDGDGGK SGCKVGVAVS INQQRLSYRL DSLKRLQITL NAVEELKDKV
EKLKTSVTSI LTERQSKYNK RYELNAMKIK VQRLRRELEQ RRSARLLEET KLESIRSSNE
IDDLVMTENT QQLAVSWDEL HEKKKGEQLI KVGTQLVHRR KYLLTDLSTI YPITKGKPDN
VITSSSPAAK RIASEPYYIC NVHLPQSENM LGQDDVMISV ALGYTAHLVS MVSFFLDVPL
RYPIRNAGSS SSVRDDIIDL LNAKEREFPL AIKGRDRFQF DYAVFLLNKN IIQLRHYCGV
ATSQLGMTLA NLYTLLNDKL GVVYNGNQSN AFISQHLHVP PSFGGPAHKT FVTRIASTTT
TTTSTVMTTS TPIAATMRMT SSTEASADAI TVGALAFPLS SMFLDSSLSE SSTSLDRTPQ
SSIIIPSHEG ITSSALTLTS TDTTTESTPL ILTTAAAATT TTTAATAAAA LETISISTSR
STESLIIPEM VEPVITYESM LPELDKILKI PQPIFGSHEF PRFINKVPLS RSTIRHQDDK
EEDDDGVNDN VDDEVNDIYG SSVLDDCNRN NDNDDGNNNN DDNNNNDNSD NIIINNNNDI
FNYEEDHRNI LKNMILNFSE TPDNCSLADD VDN
//
