ID T1HFM1_RHOPR Unreviewed; 562 AA.
AC T1HFM1;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0000259|PROSITE:PS50259};
DE Flags: Fragment;
OS Rhodnius prolixus (Triatomid bug).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Heteroptera; Panheteroptera;
OC Cimicomorpha; Reduviidae; Triatominae; Rhodnius.
OX NCBI_TaxID=13249 {ECO:0000313|EnsemblMetazoa:RPRC002843-PA, ECO:0000313|Proteomes:UP000015103};
RN [1] {ECO:0000313|Proteomes:UP000015103}
RP NUCLEOTIDE SEQUENCE.
RA Wilson R.K., Warren W., Dotson E., Oliveira P.L.;
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:RPRC002843-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; ACPB03010165; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ACPB03010166; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; T1HFM1; -.
DR STRING; 13249.T1HFM1; -.
DR EnsemblMetazoa; RPRC002843-RA; RPRC002843-PA; RPRC002843.
DR VEuPathDB; VectorBase:RPRC002843; -.
DR eggNOG; KOG1056; Eukaryota.
DR HOGENOM; CLU_005389_4_2_1; -.
DR InParanoid; T1HFM1; -.
DR OMA; KELCITM; -.
DR OrthoDB; 1331864at2759; -.
DR Proteomes; UP000015103; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR CDD; cd15045; 7tmC_mGluRs; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR000162; GPCR_3_mtglu_rcpt.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24060:SF176; MANGETOUT, ISOFORM G; 1.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00593; MTABOTROPICR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000015103};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 312..562
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 562 AA; 62836 MW; 9550B7A5D3B40794 CRC64;
GVIIFGSDQE VAAMMKAVRR MNATGIFSWI GSDGWSARDL VSNGNEPEVE GTLSVQPQAN
PVTGFEEYFL NLSVETNKRN PWFVEFWEDH FQCKYPNSSR TPYNQYTKSC TTKERLKRED
TAFENQLQFV SDAVMALAVA LEDMHRDLCG PSSGLCDLMK PTKGADLLQY LKKVTFKGLS
GDKFHFDVNG DGPARYNIIH FKQITPGNYL WVNVGEYVEG ELRLNTKDIQ FKMGQAGVPE
SVCSLPCEVG QAKTYVEGES CCWHCFNCTQ YQIRHPIEET QCVICPLGKV PDTNHEACLD
IPEVFLRPDS PWAIGAMSFS SGGILITLLV VSVFLRHNDT PVVKAAGREL TYVLLTGLLL
CYLMTFLLVL KPTDVVCGLQ RFGAGFCFTV VYAALLTKTN RISRIFNASK RTAKRPSFIT
PRSQLIICSG LVFVQVLVNT LWMLVSPPKA IHHYPTRDDN LLVCSSYVDA SYMIAFGYPI
LLIVVCTVYA VLTRNIPEAF NESKHIGFTM YTTCVIWLAF VPLYFATANH MPMRITSMSV
AISLSANVTI VCLFSPKVNR LL
//
