ID   T1HJG5_RHOPR            Unreviewed;       145 AA.
AC   T1HJG5;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   RecName: Full=ER membrane protein complex subunit 2 {ECO:0000256|RuleBase:RU367091};
OS   Rhodnius prolixus (Triatomid bug).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Paraneoptera; Hemiptera; Heteroptera; Panheteroptera;
OC   Cimicomorpha; Reduviidae; Triatominae; Rhodnius.
OX   NCBI_TaxID=13249 {ECO:0000313|EnsemblMetazoa:RPRC004188-PA, ECO:0000313|Proteomes:UP000015103};
RN   [1] {ECO:0000313|Proteomes:UP000015103}
RP   NUCLEOTIDE SEQUENCE.
RA   Wilson R.K., Warren W., Dotson E., Oliveira P.L.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:RPRC004188-PA}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (MAY-2015) to UniProtKB.
CC   -!- FUNCTION: Part of the endoplasmic reticulum membrane protein complex
CC       (EMC) that enables the energy-independent insertion into endoplasmic
CC       reticulum membranes of newly synthesized membrane proteins.
CC       {ECO:0000256|RuleBase:RU367091}.
CC   -!- SUBUNIT: Component of the ER membrane protein complex (EMC).
CC       {ECO:0000256|RuleBase:RU367091}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|RuleBase:RU367091}; Peripheral membrane protein
CC       {ECO:0000256|RuleBase:RU367091}; Cytoplasmic side
CC       {ECO:0000256|RuleBase:RU367091}.
CC   -!- SIMILARITY: Belongs to the EMC2 family. {ECO:0000256|ARBA:ARBA00010361,
CC       ECO:0000256|RuleBase:RU367091}.
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DR   EMBL; ACPB03007771; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; T1HJG5; -.
DR   STRING; 13249.T1HJG5; -.
DR   EnsemblMetazoa; RPRC004188-RA; RPRC004188-PA; RPRC004188.
DR   VEuPathDB; VectorBase:RPRC004188; -.
DR   eggNOG; KOG3060; Eukaryota.
DR   HOGENOM; CLU_1789257_0_0_1; -.
DR   InParanoid; T1HJG5; -.
DR   OMA; LFCYEEV; -.
DR   OrthoDB; 312673at2759; -.
DR   Proteomes; UP000015103; Unassembled WGS sequence.
DR   GO; GO:0072546; C:EMC complex; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR039856; EMC2-like.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR12760:SF0; ER MEMBRANE PROTEIN COMPLEX SUBUNIT 2; 1.
DR   PANTHER; PTHR12760; TETRATRICOPEPTIDE REPEAT PROTEIN; 1.
DR   Pfam; PF13181; TPR_8; 2.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50005; TPR; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum {ECO:0000256|RuleBase:RU367091};
KW   Membrane {ECO:0000256|RuleBase:RU367091};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015103};
KW   TPR repeat {ECO:0000256|ARBA:ARBA00022803}.
SQ   SEQUENCE   145 AA;  16852 MW;  27A3DADB07CFF4AE CRC64;
     MIDQEAWQEL SELYLSEQDY SKAAFCMEEL ILHNPHNHLF HQRLADIKYT QGGYDNLELA
     KSYYCQAIKL NPMNMRALYG IVLTCYNIIA SQKCTSSKKK EANNLITWAL KRIHERYRES
     NVEDNQVTAI ENLMSSLQIN SATNL
//