ID T1I812_RHOPR Unreviewed; 827 AA.
AC T1I812;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Protein transport protein Sec24C {ECO:0008006|Google:ProtNLM};
OS Rhodnius prolixus (Triatomid bug).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Heteroptera; Panheteroptera;
OC Cimicomorpha; Reduviidae; Triatominae; Rhodnius.
OX NCBI_TaxID=13249 {ECO:0000313|EnsemblMetazoa:RPRC012434-PA, ECO:0000313|Proteomes:UP000015103};
RN [1] {ECO:0000313|Proteomes:UP000015103}
RP NUCLEOTIDE SEQUENCE.
RA Wilson R.K., Warren W., Dotson E., Oliveira P.L.;
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:RPRC012434-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, COPII-coated vesicle
CC membrane {ECO:0000256|ARBA:ARBA00004299}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004299}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004299}. Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004397}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004397}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004397}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
CC {ECO:0000256|ARBA:ARBA00008334}.
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DR EMBL; ACPB03012728; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; T1I812; -.
DR STRING; 13249.T1I812; -.
DR EnsemblMetazoa; RPRC012434-RA; RPRC012434-PA; RPRC012434.
DR VEuPathDB; VectorBase:RPRC012434; -.
DR eggNOG; KOG1984; Eukaryota.
DR HOGENOM; CLU_004589_1_0_1; -.
DR InParanoid; T1I812; -.
DR OMA; INPFMTF; -.
DR OrthoDB; 977017at2759; -.
DR Proteomes; UP000015103; Unassembled WGS sequence.
DR GO; GO:0030127; C:COPII vesicle coat; IEA:InterPro.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR CDD; cd01479; Sec24-like; 1.
DR Gene3D; 2.60.40.1670; beta-sandwich domain of Sec23/24; 1.
DR Gene3D; 1.20.120.730; Sec23/Sec24 helical domain; 1.
DR Gene3D; 3.40.20.10; Severin; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR Gene3D; 2.30.30.380; Zn-finger domain of Sec23/24; 1.
DR InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR InterPro; IPR007123; Gelsolin-like_dom.
DR InterPro; IPR036180; Gelsolin-like_dom_sf.
DR InterPro; IPR006900; Sec23/24_helical_dom.
DR InterPro; IPR036175; Sec23/24_helical_dom_sf.
DR InterPro; IPR006896; Sec23/24_trunk_dom.
DR InterPro; IPR012990; Sec23_24_beta_S.
DR InterPro; IPR041742; Sec24-like_trunk_dom.
DR InterPro; IPR036465; vWFA_dom_sf.
DR InterPro; IPR006895; Znf_Sec23_Sec24.
DR InterPro; IPR036174; Znf_Sec23_Sec24_sf.
DR PANTHER; PTHR13803; SEC24-RELATED PROTEIN; 1.
DR PANTHER; PTHR13803:SF4; SECRETORY 24CD, ISOFORM C; 1.
DR Pfam; PF00626; Gelsolin; 1.
DR Pfam; PF08033; Sec23_BS; 1.
DR Pfam; PF04815; Sec23_helical; 1.
DR Pfam; PF04811; Sec23_trunk; 1.
DR Pfam; PF04810; zf-Sec23_Sec24; 1.
DR SUPFAM; SSF81995; beta-sandwich domain of Sec23/24; 1.
DR SUPFAM; SSF82754; C-terminal, gelsolin-like domain of Sec23/24; 1.
DR SUPFAM; SSF81811; Helical domain of Sec23/24; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR SUPFAM; SSF82919; Zn-finger domain of Sec23/24; 1.
PE 3: Inferred from homology;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000015103};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 158..196
FT /note="Zinc finger Sec23/Sec24-type"
FT /evidence="ECO:0000259|Pfam:PF04810"
FT DOMAIN 235..479
FT /note="Sec23/Sec24 trunk"
FT /evidence="ECO:0000259|Pfam:PF04811"
FT DOMAIN 484..566
FT /note="Sec23/Sec24 beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF08033"
FT DOMAIN 580..680
FT /note="Sec23/Sec24 helical"
FT /evidence="ECO:0000259|Pfam:PF04815"
FT DOMAIN 698..768
FT /note="Gelsolin-like"
FT /evidence="ECO:0000259|Pfam:PF00626"
SQ SEQUENCE 827 AA; 92376 MW; E9B6AE3C4678D7B9 CRC64;
MDNSGIQQNS GYGGSAHPGM PPQLSGGYAP PQPGYPQPSP YPGQQPSYPG QQQPPRRLDP
DLMPSPMQVM QDDQKTKSGI FYTNQKGLVP PLVTTDFIVQ DQGNASPRFI RATMYNVPIN
SDMMKQTSVP LGLVISPMAE VLEEEQPPPL VDFGELGPVR CVRCKAYMCP NMQFIDGGRR
FHCLLCKAST EVPAEYFQHL DHTGLRVDRF ERAELVLGAY DIVATKEYCR DNIPPKPPAL
IFLIDVSYNN VKSGLVSLLC SQMKSFLQCL PKERGEEKSS LRVGFITYNN SVHFYNLNPN
LGQPQMLVVG DTQEMFMPLL DGFLADVEES ESLIDTLMAQ IPSMFGETRE TETILAPAIQ
AGLEALKASN RAGKLLIFHS SLPIAEAPGK LKNRDDRKLL GTDKEKSVLT PQNTVYNNLG
QECVGVGCSV DLFITNNSFI DLPTIGQVAR LTGGEVYKYT YFQADLDGER LVTDVQKNIR
RLCAFDAIMR VRTSTGIRPT DFYGHFFMSN TTDVELASID PDKAIALEIK HDDKLAEEEG
VYIQTALLYT SLTGQRRIRV LNLALKSCSQ MTELYRACEL DTIINFLSKQ SVYKLLDSTP
KAVKESLIIR SAQMLACYRK NCASPTSAGQ LILPECMKLL PLYVNCLLKC DAISGGSDMS
IDDRWFTMAA VMTMDIPSSL NYFYPRLLSL HDMEDDFPSS IRCSAEKISD NGVYLLENGI
YMFLWLGLAV PSQWLMSVFG VENTALVDIE TSRLPIIDNP LSQKIRSLIS NICSSRHRSM
RLTIIRQRDK MEVVMKHFLV EDKGIDGSSS YVDFLCHLHK EIRNLLS
//
