ID T1IRJ8_STRMM Unreviewed; 1724 AA.
AC T1IRJ8;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=BRCT domain-containing protein {ECO:0000259|PROSITE:PS50172};
OS Strigamia maritima (European centipede) (Geophilus maritimus).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC Pleurostigmophora; Geophilomorpha; Linotaeniidae; Strigamia.
OX NCBI_TaxID=126957 {ECO:0000313|EnsemblMetazoa:SMAR003692-PA, ECO:0000313|Proteomes:UP000014500};
RN [1] {ECO:0000313|Proteomes:UP000014500}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Brora {ECO:0000313|Proteomes:UP000014500};
RA Richards S.R., Qu J., Jiang H., Jhangiani S.N., Agravi P., Goodspeed R.,
RA Gross S., Mandapat C., Jackson L., Mathew T., Pu L., Thornton R., Saada N.,
RA Wilczek-Boney K.B., Lee S., Kovar C., Wu Y., Scherer S.E., Worley K.C.,
RA Muzny D.M., Gibbs R.;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:SMAR003692-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (FEB-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC {ECO:0000256|ARBA:ARBA00009995}.
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DR EMBL; JH431367; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 126957.T1IRJ8; -.
DR EnsemblMetazoa; SMAR003692-RA; SMAR003692-PA; SMAR003692.
DR eggNOG; KOG1192; Eukaryota.
DR eggNOG; KOG2408; Eukaryota.
DR HOGENOM; CLU_240180_0_0_1; -.
DR OrthoDB; 382054at2759; -.
DR Proteomes; UP000014500; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004601; F:peroxidase activity; IEA:InterPro.
DR GO; GO:0008194; F:UDP-glycosyltransferase activity; IEA:InterPro.
DR GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR CDD; cd09823; peroxinectin_like; 1.
DR CDD; cd11655; rap1_myb-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR Gene3D; 1.10.640.10; Haem peroxidase domain superfamily, animal type; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR019791; Haem_peroxidase_animal.
DR InterPro; IPR010255; Haem_peroxidase_sf.
DR InterPro; IPR037120; Haem_peroxidase_sf_animal.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR015010; Rap1_Myb_dom.
DR InterPro; IPR002213; UDP_glucos_trans.
DR InterPro; IPR035595; UDP_glycos_trans_CS.
DR PANTHER; PTHR11475:SF106; CURLY SU; 1.
DR PANTHER; PTHR11475; OXIDASE/PEROXIDASE; 1.
DR Pfam; PF03098; An_peroxidase; 1.
DR Pfam; PF08914; Myb_DNA-bind_2; 2.
DR Pfam; PF00201; UDPGT; 1.
DR PRINTS; PR00457; ANPEROXIDASE.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF48113; Heme-dependent peroxidases; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
DR PROSITE; PS50172; BRCT; 1.
DR PROSITE; PS50292; PEROXIDASE_3; 1.
DR PROSITE; PS00375; UDPGT; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|PIRSR:PIRSR619791-2};
KW Iron {ECO:0000256|PIRSR:PIRSR619791-2}; Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR619791-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000014500};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..1724
FT /note="BRCT domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004579447"
FT TRANSMEM 466..491
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1166..1227
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 1338..1359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 917
FT /ligand="heme b"
FT /ligand_id="ChEBI:CHEBI:60344"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000256|PIRSR:PIRSR619791-2"
SQ SEQUENCE 1724 AA; 196026 MW; BA63EF2E54DF6008 CRC64;
MLKHFLILLL IFNVTTAGDV LMLVPFGSMS HKICFDPIAR ELGARGHNVT LISVFEPTKT
YPNVNEIVIP AMVHLHRQLQ DGHVRVGKEG VTYAIWSMFG DICGELCDNF FQTGMLQEWL
KNGRKFDAII VDSVMAECLV SVAHLLSPAV VLWNTAFLLP WVAIPSDIPT PSSYNPYSFD
GSIAQMSLWQ RMWNVVAHEK SQLLFNHAMY PPMDRAVFRH FPQATSIVEA MRRLSLILVN
GNAVLSTPRA EMPVVVNVGG LHLTPSKPLT PDFAQLVDSA VNNGVVIFSL GTIFDALLTP
DREEIIFKTQ ISNYMEIQKK FENTPKNIKI FEWIPQKDLL AHKNIRAFIT HAGLLSLQEA
FHNQVPTVTL PVFADQPQNT AFLTSLNLTI PLSWDTLSVE NIIDAVTRAA EDETLRQNVA
RVSRIFKDTS ESPLNKSVFW MEYIMRHKGA PLLQPAAKEL NLIQYFIIDV LLFLFFILVL
VVLCNGLMAF LAENERDVFP VEYLPNIDDL LVDRVVDIAK RQIEDEAKLN VDSHFHSKRN
GKVKEEVWEI HKQVSIGARA VDILSSEQNL TREASDHIVK RAPPRNGINF NVLCEDRRFQ
CNRFAKFRNL DGSCNNHANP DWGMAVHKQN RLLAAKYGDG FNTPRVAKSG RRLPLSRFVR
TTTIPDISAE SDRITHMIVQ FGQFMNHDIT STPDRTDLTN CCSNPNRMDC LPLLIPRDDP
DLSQLQIGCM EFSRSIRACG NGVRQQINQN TAFIDGSQIY GSSEAESSSL RTFRQGLLQS
SNNGENLPVN PTDQGCATRG TGTNFCFRAG DNRLNIQPGL SSMHTLFMRE HNRIARILLR
FGPRFNDETL FQETRRVVIA ELESITFNEF LPLVLGPDLM KQYDLTLPKT GTATNYKSNV
DPRIINSFTS AAFRFGHSQI LNFGQLGTFR NGFALKDNFN DPTVVHRAGA DSVLVGSVIQ
KAEGMDNFMV EAVTKFLFKQ GNNPVGLDLG AFNIERGREH GIPSYNDFRE FCELPRIKTF
EGLSDVFKDS RAPRAFELAY EDVDDIDLFP GGIAEKSVPG GLVGPTFACI IGTQFHRLFH
GDRHFYTHGN QPGSFTSDER AMLSKRTLSS VMCDNLDVES VQLNAFLASN NSKNPLDIKM
EKYTHNPYLF YLDDQPLRFS MRPCDERIKL KPVVEHGGAT ITSKSTKDTF RLVPPGAIVS
TDDCISTKWI WDCVKENKLL STEDYIVKQR VESDVSDIDE GDNVVRMVNK KRKSPKGTRK
EYLLCEDMAI INYLFDNRRI GEVKARAMWQ EMERVNVVPD RSWQSLKERY NKQIADNLQS
YNLTKEKLKY LKYKETINRT PPKRPPLRPK STPSPTASEI SFTRRQTRLY TVEEDTKLIY
YVLDEDDHRA IMGNIFWKKA AARKVLDRTW QSMRERFLKY IVYDMKKYKI KYEYRKSLGR
LLHQVGVVYD SPIEISDDED GKIVKNKEKN VLKSPNVEIL IENTEDDELI REAEEDIRDQ
RNDLESPDLQ LRLEESDDEV ENNHRMEKIC LEESPEIGKF VLERSKSPEV ENKDEICDKN
TAAILEKIIT DDNENLVVLD YVTSTNGSPK LEITLFHLIR VNSSAQTQDL VGESSINNQP
VVKNGEMNGD NTGKRKRLAI PNANLNFKRL NSGKMARPSD DEEEDFAKVA DEIERLGQQN
LDEVDTNIKV LSVLFGLTED QTWQLLESVD FDRSTLLKEI CGIL
//
