ID T1J837_STRMM Unreviewed; 1885 AA.
AC T1J837;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Down syndrome cell adhesion molecule-like protein Dscam2 {ECO:0008006|Google:ProtNLM};
OS Strigamia maritima (European centipede) (Geophilus maritimus).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC Pleurostigmophora; Geophilomorpha; Linotaeniidae; Strigamia.
OX NCBI_TaxID=126957 {ECO:0000313|EnsemblMetazoa:SMAR009858-PA, ECO:0000313|Proteomes:UP000014500};
RN [1] {ECO:0000313|Proteomes:UP000014500}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Brora {ECO:0000313|Proteomes:UP000014500};
RA Richards S.R., Qu J., Jiang H., Jhangiani S.N., Agravi P., Goodspeed R.,
RA Gross S., Mandapat C., Jackson L., Mathew T., Pu L., Thornton R., Saada N.,
RA Wilczek-Boney K.B., Lee S., Kovar C., Wu Y., Scherer S.E., Worley K.C.,
RA Muzny D.M., Gibbs R.;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:SMAR009858-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (FEB-2015) to UniProtKB.
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DR EMBL; JH431948; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 126957.T1J837; -.
DR EnsemblMetazoa; SMAR009858-RA; SMAR009858-PA; SMAR009858.
DR eggNOG; KOG3510; Eukaryota.
DR HOGENOM; CLU_001038_4_0_1; -.
DR OMA; SRECKLR; -.
DR OrthoDB; 2405257at2759; -.
DR PhylomeDB; T1J837; -.
DR Proteomes; UP000014500; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd00063; FN3; 6.
DR Gene3D; 2.60.40.10; Immunoglobulins; 16.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR44170:SF30; FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 6.
DR Pfam; PF07679; I-set; 6.
DR Pfam; PF13927; Ig_3; 2.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 6.
DR SMART; SM00409; IG; 9.
DR SMART; SM00408; IGc2; 9.
DR SUPFAM; SSF49265; Fibronectin type III; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 9.
DR PROSITE; PS50853; FN3; 6.
DR PROSITE; PS50835; IG_LIKE; 10.
PE 4: Predicted;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014500};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1590..1612
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 4..97
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 118..194
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 207..295
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 299..385
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 391..475
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 483..563
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 575..665
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 670..763
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 766..874
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 881..977
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 981..1079
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1084..1184
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1188..1284
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1280..1371
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1375..1468
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1472..1564
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1808..1885
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1849..1874
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1885 AA; 209514 MW; DE00AEFBAADE0E8A CRC64;
MVGPLFVTEP PYRLDFSNSS GARLDCLAHG VPPPRISWHT GDGSLVADVV RLRKVYSNGT
VMFPPFRAED YRQDVHANVY LCLASNSVGS IISREVNVRG VAKQYYELQV YDEFVIVENT
GVLRCHIPSF VEDYVSVASW VREDGLVHGR NNNGGRFFLT ANGDLYVANV VSSDMNKTYR
CKTLHRLTGE VRLSSPGRII PKSSVPPRIT HTKPLIQIQE GATVELPCAA QGFPTPSYRW
LRVLGKDAVP VQQDPRVRQV LSLLVLDKVH SEDAGVYRCL VFNSMGEEKT EVVLRVTAPL
SVHVSPQRQT VDVGKECRMS CVVNGFPVTS VAWVKNGKSL IETERVKFIS REMVEIMEVQ
KEDKGMYQCL VGNGEEMAQG AAEIKLGNVA PAVHLTYPEK PMRSGSPVTI KCVAFGNPPP
EISWQVDDIQ LPPQPFFHTA NGETVSHLNL TRARLEDGGE YRCIAKNPGG KREIAGRIQI
IGPPLVLPMK NITAVAGKSI TIKCRVTGHP LDSISWERDG NVLPTDHRQK IHENGTLHIH
QVDRATDQGI YTCIAQNRQG IVSRNWLGLF VKVAPTIGPF SFPPVVRDGM RARLQCVVTQ
GDLPIVITWL KDEHRIPHDL GLTVRQDDDF SSTLTFQSVS PRHSGRYRCI ASSEVGTANY
SATLVVDVMP KWVIQPGNKA IVVRGQVTLD CQAEGYPEAI ITWKKAIGKY ETLVEMTQTG
FRENFVDLNR TGPRYKHFPN GSLLLMAVTE ADEGYYMCHA SNGVGPGLSK VVYVTVQASA
HFEEKKRNHT AKKGDSVKME CRATGDSPIS ITWQSNSREF FPKDDSRFIV KEKPLPNGML
SEMTILNANR KDSGTYSCTA RNTFGHDQMI TRLTVLESPE APENVKIADH GSRLVKLLWS
APFDGSSPID KYIIQYKNGS EEWAKSLPNV TVTGQETTAV IRNLLPGTAY SFRVMAANEL
GIGKPSSGVG ISTTEEAPAG FPQDVQVTAL SSDSLKVTCK PPGKSLWNGE ILGYVVSYRA
HQSKELLRMK TLEAFSDMSA EIVLDGLQKY TKYSVIVQAY NRMGRGPATA EIFAFTAEDV
PSKPPNNIRC RSIASQMLQV EWEEPPLDSQ NGVLLGYKVL YDLVADVADD VDENGSEQLL
STSEHLISLY ELMKFANYSI RVLAYTKMGN GVISNSIYCM TKEDVPSPPA KIKALVVSSE
SIRVAWKIPS HPNGRIIKYN VYMRGLEKEN KKTLKHTIAD PGIHHFEAKG LLPDTNYEFW
VTASTQVGEG ESTKVITQKP TRKTAASISS FSEPLVVSWQ QNITLECHTV GMPKPITGWT
LKGESWTDDS RAVILENNSI FLTEVQRQDA GNYSCFAENK YGKDEIQYSI YVMAPPLPPT
LTIVWETTSS IGLMWKAAGD GGSKIKGYVL NYKQDYGKWL EVQLLATDDK YSLDNLLCGT
RYHLNLAAFN QVGLGNMSTT VTAATKGSRP LLPRQEEVVT ANATLLTIRL VRWPDGGCPV
LYFVVEYKSR DEQKWLLVSN NLAPQHEVVV VPDLRPETWY AVRVTAHNEA GSTIARFDVA
TLSYAGGTVG PGVLVKSPSS ALPFYRDVSV ILPIVISTMI TLTTLFGMCL CLHRRRGVLL
RQEVGTPEKK AALTADYDAS RGSTGVRKVH PPSSCDINRG VHLNSANPSE DVCPYATFRL
PSHANKESEE TYQLQNFTLL AEKGVLCNSQ HRPSSDFRRE DIYSKVNKRP SSKTTEENQI
YKKADEIRPY LPRDVQMSPG QGYKLPDYDT VNHSPEMSNY NRISNGPVPR TVNVEHPWNQ
YGKQTHRFPD LLYHGPESNS SDDMEEDGDI EEDDENPDKC RWTNPKETLI GWSDPNVSQQ
FQQTWRTPMS SSGYDKRAAQ RLLSP
//
