ID T1JAC9_STRMM Unreviewed; 2027 AA.
AC T1JAC9;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Down syndrome cell adhesion molecule-like protein Dscam2 {ECO:0008006|Google:ProtNLM};
OS Strigamia maritima (European centipede) (Geophilus maritimus).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC Pleurostigmophora; Geophilomorpha; Linotaeniidae; Strigamia.
OX NCBI_TaxID=126957 {ECO:0000313|EnsemblMetazoa:SMAR010689-PA, ECO:0000313|Proteomes:UP000014500};
RN [1] {ECO:0000313|Proteomes:UP000014500}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Brora {ECO:0000313|Proteomes:UP000014500};
RA Richards S.R., Qu J., Jiang H., Jhangiani S.N., Agravi P., Goodspeed R.,
RA Gross S., Mandapat C., Jackson L., Mathew T., Pu L., Thornton R., Saada N.,
RA Wilczek-Boney K.B., Lee S., Kovar C., Wu Y., Scherer S.E., Worley K.C.,
RA Muzny D.M., Gibbs R.;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:SMAR010689-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (FEB-2015) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH431989; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 126957.T1JAC9; -.
DR EnsemblMetazoa; SMAR010689-RA; SMAR010689-PA; SMAR010689.
DR eggNOG; KOG3510; Eukaryota.
DR HOGENOM; CLU_001038_4_0_1; -.
DR OMA; DGFDHHK; -.
DR OrthoDB; 4503820at2759; -.
DR PhylomeDB; T1JAC9; -.
DR Proteomes; UP000014500; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 6.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 17.
DR InterPro; IPR040676; DUF5641.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR44170:SF30; FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF18701; DUF5641; 1.
DR Pfam; PF00041; fn3; 5.
DR Pfam; PF07679; I-set; 4.
DR Pfam; PF13927; Ig_3; 5.
DR SMART; SM00060; FN3; 6.
DR SMART; SM00409; IG; 10.
DR SMART; SM00408; IGc2; 10.
DR SUPFAM; SSF49265; Fibronectin type III; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 11.
DR PROSITE; PS50853; FN3; 6.
DR PROSITE; PS50835; IG_LIKE; 10.
PE 4: Predicted;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014500};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1743..1765
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 54..153
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 272..363
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 365..447
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 453..543
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 548..634
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 639..735
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 739..831
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 836..921
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 931..1028
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1033..1128
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1133..1231
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1236..1339
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1343..1438
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1455..1520
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1529..1622
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1626..1718
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1875..1914
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1887..1914
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2027 AA; 222836 MW; C1A5483E9BBBEC44 CRC64;
MHRNVKIGDV VLIQDENQPR SSWQMGQVEQ TFLGRDNKVR SCEIRLSTGK VEAPALTSVE
LHGPVFIQEP TNHVDFSNTT GARVECTAHG TPLPAVQWLL ADGSPASDVP TVRVVYSNGT
LAFLPFPAEG YRQDVHAAIY RCRASNSVGA ILSRDVRIRA VVMQMYEVQV YNEFVIRGNT
AVLKCHIPSF VTDYVKVMSW VRDTTFNVLS EVETGGRYTI MPTGELHIRE VGPSDAYHSF
RCRTIHRLTG EIRISSMGGK LVISDPQGSV TPRITDSKTL VQIHKGEAAL LPCAAQGYPA
PTYSWYVKSN RSQMNSLVLT DRIKQIGGSL LIQNARIADG KTYVCVVSSN VGNQSAVTVL
SVTVPLSAYI QPHKLKVDVG SSAVLNCKTS GYPVASLVWL KDAQLVRPQP HPPHSLHIET
LRREQRGMYQ CMASNDHEAA QGTAELRLGD AASDIVEGFQ ERVLSPGTST SLRCVASGNP
APQMMWMLDD TPLVNSLHTE LVSAQGEVVS YLNLTGVRTQ DGGDYTCLAS NRLGNSSHTS
RLNILGPPGI RPMSRMSVVA GFDVTLKCRV YGHPLESLSW EKDGLLLPVN RRQKLFPNGT
LAIQNIQKTI DGGKYACVVR GVTGEAVRKD MEITVMVPPK ISPFSFQDED LYEGMRAQVT
CAVRQGDLPM AIHWMKDGVP IEATSLGRDG ALVARTFDVY TSSLSIDSVA SEHNGNYTCV
ASNMAAAVTY SSSLRVNAPP VLASFSFPSV GIHEGMVARV TCSVTQGDLP IYFHWAKDGR
QIASGEGIAI KDFDEYASIL TINDVRHRHT GRYTCIANNA AASIKHSTHL IVHVPPRWLV
EPKDTQVLVG ASARMDCQAD GYPEPSITWT KALPSDYREI LGNGGNVNIL QNGSLILSSI
REVDRGYYSC QANSKVGEGL SKVFFLDVHV PVQFEVRSRN QTAKRGENVR LQCNAKGDSP
IKVTWSVNSH PIEPAARPRY KIKEMSSKHG FLTELIVTRS ERSDSGVYSC SATNPHGRDS
TVIHLTIQEP PEAPRSVNVE DYDARSVNLA WLQPYDGNSQ VAKYIVQYKH VLADWIGGSA
NETVIGRVTS AVVSSLLPAT KYAFRVMAEN EVGVSEPSET VVISTAEEAP SAPPTHILIE
ATQPQCLKVS WKAPQKDLWH GEILGYNVGY KMQDSSKPFL FKAVESASLD GGHLELRGLL
PFTKYDIVVQ AYNRVGPGPL SDAIGASSAE EVPSRAPDDV RCSAHSSQSV HVTWAPPSPQ
SVNGILQGYK LLFREIHEQK RHQTLGHDNS IMETKITPSL ETILHGLAKF QNYSIQVLAF
TRVGDGVKSD VITCQTFEDV PESPEKVKAL VASEDSILLT WLPPSQPNGI IIRYTVYIRT
IDKDKENTTK MIVSGSQLSY DFKGLVKNHR YEFWVTSSTS IGEGQSTKMV SVTLTSKVAA
KIVSFGASIV IAWKEDVHVT CDAVGIPPPT RVWNVGGQPL PQLERYQVQP DGSLLVRNVQ
LTDSGNYSCR VENGHGSDIN FYIILVQAPP VPPHVAVSSA TSSSVTIHWK PGPDGGSAIT
GYSLTFKRDY AEWEEIQLNA DRRSHVLNNL WCGSRYQLYM SAANVIGAGE PSEIASIKTK
GSAPSAPAKE QLIYPNAEFV ALNLNTWDDG GCAILYFIIE YKAKSSPDWV LVSNNVKPQR
DAFLIPDLES RVSYNVRITA HNSAGSQTEV YDFATRGRSD IAQDDKSDMD EEDQAPFYAD
LKLIVPIASA ILGLLVIFAT YALCISFRRN KLHDKNESEN YSQPEKDVGS SLAHEFDKNS
VQTPVSTRCN YLQQEFDHFP GSLAAPTRPK LNYTQTSLED VCPYATYRIP ESSNKAQVHT
SAWHQLPLKT QDFLSGGREK RDCGKQTSSN KNFSPQVTDQ ESTNYQNPIT SCDQINHQTS
SNYPITSPNH RQVAALNLEA NIPDLLYHGT ESSTSNDTSP DLEWGMYNSM GRNMKFLPRI
SAQPKFAAID SNIGHDHGRM FSKDVTAPTM EADFIDVMRN DLRNSRV
//
