ID T1JFU9_STRMM Unreviewed; 1309 AA.
AC T1JFU9;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Nucleolar protein 6 {ECO:0000256|ARBA:ARBA00016437};
DE AltName: Full=Maternal transcript 89Ba {ECO:0000256|ARBA:ARBA00031711};
OS Strigamia maritima (European centipede) (Geophilus maritimus).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC Pleurostigmophora; Geophilomorpha; Linotaeniidae; Strigamia.
OX NCBI_TaxID=126957 {ECO:0000313|EnsemblMetazoa:SMAR012714-PA, ECO:0000313|Proteomes:UP000014500};
RN [1] {ECO:0000313|Proteomes:UP000014500}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Brora {ECO:0000313|Proteomes:UP000014500};
RA Richards S.R., Qu J., Jiang H., Jhangiani S.N., Agravi P., Goodspeed R.,
RA Gross S., Mandapat C., Jackson L., Mathew T., Pu L., Thornton R., Saada N.,
RA Wilczek-Boney K.B., Lee S., Kovar C., Wu Y., Scherer S.E., Worley K.C.,
RA Muzny D.M., Gibbs R.;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:SMAR012714-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (FEB-2015) to UniProtKB.
CC -!- FUNCTION: Part of the small subunit (SSU) processome, first precursor
CC of the small eukaryotic ribosomal subunit. During the assembly of the
CC SSU processome in the nucleolus, many ribosome biogenesis factors, an
CC RNA chaperone and ribosomal proteins associate with the nascent pre-
CC rRNA and work in concert to generate RNA folding, modifications,
CC rearrangements and cleavage as well as targeted degradation of pre-
CC ribosomal RNA by the RNA exosome. {ECO:0000256|ARBA:ARBA00035000}.
CC -!- SUBUNIT: Part of the small subunit (SSU) processome, composed of more
CC than 70 proteins and the RNA chaperone small nucleolar RNA (snoRNA) U3.
CC {ECO:0000256|ARBA:ARBA00035020}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the NRAP family.
CC {ECO:0000256|ARBA:ARBA00006674}.
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DR EMBL; JH432185; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 126957.T1JFU9; -.
DR EnsemblMetazoa; SMAR012714-RA; SMAR012714-PA; SMAR012714.
DR eggNOG; KOG2054; Eukaryota.
DR eggNOG; KOG3317; Eukaryota.
DR HOGENOM; CLU_003502_1_0_1; -.
DR OMA; NPHGGKE; -.
DR OrthoDB; 276928at2759; -.
DR PhylomeDB; T1JFU9; -.
DR Proteomes; UP000014500; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1410.10; -; 1.
DR Gene3D; 3.30.70.3030; -; 1.
DR InterPro; IPR005554; NOL6/Upt22.
DR InterPro; IPR035082; Nrap_D1.
DR InterPro; IPR035367; Nrap_D2.
DR InterPro; IPR035368; Nrap_D3.
DR InterPro; IPR035369; Nrap_D4.
DR InterPro; IPR035370; Nrap_D5.
DR InterPro; IPR035371; Nrap_D6.
DR PANTHER; PTHR17972:SF0; NUCLEOLAR PROTEIN 6; 1.
DR PANTHER; PTHR17972; NUCLEOLAR RNA-ASSOCIATED PROTEIN; 1.
DR Pfam; PF03813; Nrap; 1.
DR Pfam; PF17403; Nrap_D2; 1.
DR Pfam; PF17404; Nrap_D3; 1.
DR Pfam; PF17405; Nrap_D4; 1.
DR Pfam; PF17406; Nrap_D5; 1.
DR Pfam; PF17407; Nrap_D6; 1.
DR Pfam; PF05753; TRAP_beta; 1.
PE 3: Inferred from homology;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000014500};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1274..1293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 142..295
FT /note="Nrap protein"
FT /evidence="ECO:0000259|Pfam:PF03813"
FT DOMAIN 304..431
FT /note="Nrap protein"
FT /evidence="ECO:0000259|Pfam:PF17403"
FT DOMAIN 436..595
FT /note="Nrap protein"
FT /evidence="ECO:0000259|Pfam:PF17404"
FT DOMAIN 616..797
FT /note="Nrap protein"
FT /evidence="ECO:0000259|Pfam:PF17405"
FT DOMAIN 802..954
FT /note="Nrap protein"
FT /evidence="ECO:0000259|Pfam:PF17406"
FT DOMAIN 957..1067
FT /note="Nrap protein"
FT /evidence="ECO:0000259|Pfam:PF17407"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1309 AA; 148578 MW; 14C28843EE0BE1C0 CRC64;
MDLDGERPEK KIKGKDGKAK NKKTDNPTIS REEINQLVQN ESYFPSSFFR LQSEELLLQV
RVRDKTKKRF DEWFADFKQF VYSEKSAENV DLTNDECKSL APALSRCANP VKKENIFYQP
PDEMKLIGSF PLGVAIESTT SVDVMVRIPK VDDKFNQLKY FYNGDNLDLR YFYKRALYIE
HLAKLLAKAD DLIQEMYREY HHGDQLKPIL VIRPKGFSNM LVKLLPCPPS NRFKLSKLEP
SRNNIRHEWM TGEKRETETE TETETETELA TPRYNSCLLS DISMESCFDY LQNILTTNQN
ISGGIMLLKV WLHQRQLDQG FGCIGNFILT SFVARLLENS GRKLHPLMSS YQIARNTWLA
LSKSDWTQAG TEHLESAEFF LYFPVVLLDS TRTFNLCANV SKSTYLRLKH EAELAVKLAD
RAKHFDELFM DPVPFIRKFD HVLRIDAEIN YSLIIEKFNL ADRYTDHIGD EKSIVLPTII
DILRRALGER IDLLDVKLQT SLPWKVDEYP SIPDDGITFG LLLNPEHYCS VLDKGPSAET
ERAEEFRQFW GPKSELRRFQ DTSVCEAVTW PGSSVSEKRT VCKNVAEYIL RRHLNIRNNR
ITYVANQTES FVARGNGTGE ELAVNVMAVL DKLRQQIEKA NGLPLAVTSV QGVSASFRYT
EVCPPRPLKC ISNSTNFGSA RKSFDALDVL ITMEGSNKWP NDADAVRRIK AAFYIKLAHV
LKEQYGLCCV PTAERAFVFK EGFMFAISIG YKRESVLVKM KRSADGMLKL LENEKSVALE
KDVVQLPKIT STLHGLQLQQ GSFGCACRLA KRWISAQLLA DHVSDMAVEL TMAYIFVSPA
PYTPPKSPQV AFQRWLDLIA RHNWKDVPLI LDVNEELTPA DRDEITKYFS DNEKSLPPLF
IATPFDKFTS CWTKNAPCLP VLNRLIKLAA AGRRLMETEL ENSRSPDLLP LFRPSYEPYD
VLIRLNPKKT PRVHESIPIV DYDPASRYLK ELGRAFDDYA AFFYDKYGGD TIAVLWKCKN
FRPVEFKVSG ANCKKPADVE NEDNATLAVD VEAIVEDFTI LGKGLVRFVD VALDRKNFRV
SASAGHAHSL TTASHTRRKQ LSTNLAMIRC LLAIFVSCLI VRSGAADEEA SQARLLVSKQ
ILNKYLVEGK DVLVSYTIYN VGGSAAYNVL LTDSSFDANH FQVISGLLKM KIDRIPPGTN
TSHTVVLRPT MYGYLNFSAA EIRFRSSESS AAQQVGFSSE PGEGGIVPFK DYNRKFSPHA
VTTNNVVNNL PLDWIAFAVM TLPSLGIPFL LWFKSKSKYE SLTKPTKKH
//
