ID T1JGC8_STRMM Unreviewed; 631 AA.
AC T1JGC8;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=NTF2 domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Strigamia maritima (European centipede) (Geophilus maritimus).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC Pleurostigmophora; Geophilomorpha; Linotaeniidae; Strigamia.
OX NCBI_TaxID=126957 {ECO:0000313|EnsemblMetazoa:SMAR012900-PA, ECO:0000313|Proteomes:UP000014500};
RN [1] {ECO:0000313|Proteomes:UP000014500}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Brora {ECO:0000313|Proteomes:UP000014500};
RA Richards S.R., Qu J., Jiang H., Jhangiani S.N., Agravi P., Goodspeed R.,
RA Gross S., Mandapat C., Jackson L., Mathew T., Pu L., Thornton R., Saada N.,
RA Wilczek-Boney K.B., Lee S., Kovar C., Wu Y., Scherer S.E., Worley K.C.,
RA Muzny D.M., Gibbs R.;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:SMAR012900-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (FEB-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus, nucleoplasm {ECO:0000256|ARBA:ARBA00004642}.
CC -!- SIMILARITY: Belongs to the NXF family. {ECO:0000256|ARBA:ARBA00009285}.
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DR EMBL; JH432201; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; T1JGC8; -.
DR STRING; 126957.T1JGC8; -.
DR EnsemblMetazoa; SMAR012900-RA; SMAR012900-PA; SMAR012900.
DR eggNOG; KOG3763; Eukaryota.
DR HOGENOM; CLU_011280_2_0_1; -.
DR OMA; YGGHEAW; -.
DR OrthoDB; 21687at2759; -.
DR PhylomeDB; T1JGC8; -.
DR Proteomes; UP000014500; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0006406; P:mRNA export from nucleus; IEA:InterPro.
DR CDD; cd14342; UBA_TAP-C; 1.
DR Gene3D; 3.10.450.50; -; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR InterPro; IPR002075; NTF2_dom.
DR InterPro; IPR018222; Nuclear_transport_factor_2_euk.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR030217; NXF_fam.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR005637; TAP_C_dom.
DR InterPro; IPR015245; Tap_RNA-bd.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR10662; NUCLEAR RNA EXPORT FACTOR; 1.
DR PANTHER; PTHR10662:SF22; NUCLEAR RNA EXPORT FACTOR 1; 1.
DR Pfam; PF02136; NTF2; 1.
DR Pfam; PF09162; Tap-RNA_bind; 1.
DR Pfam; PF03943; TAP_C; 1.
DR SMART; SM00804; TAP_C; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF54427; NTF2-like; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS50177; NTF2_DOMAIN; 1.
DR PROSITE; PS51281; TAP_C; 1.
PE 3: Inferred from homology;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000014500};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 384..540
FT /note="NTF2"
FT /evidence="ECO:0000259|PROSITE:PS50177"
FT DOMAIN 575..630
FT /note="TAP-C"
FT /evidence="ECO:0000259|PROSITE:PS51281"
FT REGION 1..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 82..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..31
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..63
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 631 AA; 71348 MW; 33E69D2E2BACF208 CRC64;
MSDLKFRVSR DQGPRTTYYQ HDDRDERIVK FKSNGNGGGR RRRRDNHLKQ PDGRSAFYDE
EGDVQMDADI EPSRKSRFVP YEARGGFSRG KNRRQQRRWG RGCNDGGYNQ RNDRNSRSNS
NWFRIVIPKG NIADKNTILK ILAQKSQVPF IPFNFVYEGN YAIFHVEGRE CAKAIERLNG
EISFNGIKMT IKIYPSSQPP EVKLDDFILN KIKEVMSKRC NMDAKTLDLS SFVNDIDLKN
NGIYISLNRQ IVFSSIIELI EGNIPDLVSL NLTDNKLTSE QLRLLKKLKN IKCLLLGGNN
LRSLNDLDSI KELSLEELVV SRNPLCDHNK DQAAFVSAVR QKFPKVVRLD GQELPPAYGF
DVEPETILPT SQGNFFSDET VRGIVPQFLE QYFTFYDSGD RQNLLAAYHD QAVFSMSAVS
FLKGGMSAGN TSSNQFQTTY IHESRNLLIV KPLSRRQKLL RQGKISIISY LCQLPKTQHD
PMSFSIDVPH FSNSLLTVSC SGVFKEVDSK PGTPIRAFSR VFILVPQGAG FCIINEMLFV
THATSDQAKT AFKVPAPTPS PSPVPPSLTS APSALDQEQM VLMFSQSSGM NIEWSTKCLQ
ENDWDFHKSA NVFQEYNTKG QIPPAAFIKS I
//
