ID   T1JWM7_TETUR            Unreviewed;      1402 AA.
AC   T1JWM7;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE            EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
GN   Name=107371782 {ECO:0000313|EnsemblMetazoa:tetur02g08820.1};
OS   Tetranychus urticae (Two-spotted spider mite).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Acariformes; Trombidiformes; Prostigmata; Eleutherengona; Raphignathae;
OC   Tetranychoidea; Tetranychidae; Tetranychus.
OX   NCBI_TaxID=32264 {ECO:0000313|EnsemblMetazoa:tetur02g08820.1, ECO:0000313|Proteomes:UP000015104};
RN   [1] {ECO:0000313|Proteomes:UP000015104}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=London {ECO:0000313|Proteomes:UP000015104};
RA   Rombauts S.;
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:tetur02g08820.1}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC         ECO:0000256|RuleBase:RU363098};
CC   -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC       ECO:0000256|RuleBase:RU363098}.
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DR   EMBL; CAEY01000813; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_015795432.1; XM_015939946.1.
DR   EnsemblMetazoa; tetur02g08820.1; tetur02g08820.1; tetur02g08820.
DR   eggNOG; KOG0988; Eukaryota.
DR   HOGENOM; CLU_253544_0_0_1; -.
DR   Proteomes; UP000015104; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProt.
DR   InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR   PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR   PANTHER; PTHR23079:SF55; RNA-DIRECTED RNA POLYMERASE; 1.
DR   Pfam; PF05183; RdRP; 1.
PE   3: Inferred from homology;
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015104};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU363098};
KW   RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW   ECO:0000256|RuleBase:RU363098};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
SQ   SEQUENCE   1402 AA;  158907 MW;  C6B7018C9FC0E990 CRC64;
     MPTQMLSPVS FELEIVHSKK RLLHIVNVLL YIKNIFIDSK VTSAEITDNR GNKHRYSEGS
     FSSTWCDKPR DSPSKSVQWK GTVDLKTNQL GDLISNISPR RGKIDDSYGY FWRFDENSYN
     FRQVIGTKSS NSKLPSNIAN FAFGNIVNGD CFVSHFSTQS SPKIADLNVE LVSHKNELNL
     MFTVIDETGT KKKVKFRYDC DSIKSAIIHH VRPFGFSLYA ALSNAPKMFV ADGQSCFING
     RNQINWKRKS SCGPISRDLI GKCNVLRLTW VYHDTSYMPA LYLWRRHLKF DLSFGSIINC
     SNFLVDESID MEFPDKIGYL LACLKSWSYN YQDDLHINYE GEAIINEFIK KQISAGKSDQ
     VQRALHHLHE SIVNCKVINV FEHFKDLLNK VELEWTNIKD LEKDTEHIKY VKTGVFTPSR
     TVFMPPVMTR TSKFLDSAEI DCVLRVIYRD ENSGPLSSTF NNFGFNQQKG KRYDEENVDC
     VTSMLKHRLL KNGLCVAGRT YQYFGASPSQ LKDGGMMLYS KDSQNRTAAS IRSSLGIVKE
     KSVPKYMSRI GLSLSQVMAF VDLPGYTKIY LTSDIYGGSH PHTNKPYNFT DGCGSISLEA
     ARYIYDDLIR QKVLERKGDD CYIPSAFQIR FMGSKGMLVV DPDLIGMTIV IRESMQKMFT
     ERDRLGIVKV SEPRRAYLNK PFIMVLNQIG LCHDFFINLT TTTLRDLNSS FYDEQVALMT
     MKLYTHLNRV VSIDAFANCN FSFTNDSFFQ AILHLAVKQA FDSLKTKQRI PLPWFEARTM
     LGVCDTTAKS PKVLANFEKG ICQPSKLPVS MDGLGTGALK EGQVFCWPSD FPEPLRGEVI
     VTKFPTSDLG GVRRLVAVDC KQLHAIRDCI VFPVDGKRPH QDEMAGSDLD GDEYCVIWME
     DILGIQERIP MTYPDNPKAK TQDEISDERM IEHHINCVKS DQVGQISNAQ LALADSKGYD
     SDLCKSLGYK YNGALDAPKN GFDSRYLLRR GDRPLETPDY MDKWSIKPTY YSTSACGEIY
     RLVNLHQLSS IFLNVPAVFE PSSDIDERLL HPRMLKFITF AAESLLVYES RINHLLTRYG
     LKSEVELFTG ILDGSSPSLL NESSRIKDKE DAMVAVLNSL LINKMDELFD SKLINASEDD
     KMAAASAIYY VSKQKVKETT TSYIGLPFIG NCAFYLRKYM KYKATTKKRE KTPTTKAVVT
     HNQSTIEHPL MASAICKIKD KVINIIETFL TYGKGPKHTT LAISSRIDKV MSRDDPCAVV
     SLPVNILIAK LIQETKLVWT NLTGQKNNEL NLNQFINTTI PTLIRSLLVD GTSLYKNEKT
     TSDYINQSFQ VNYCKRGTHD LLWTLLEKTL AADTQIEILS DSMEKNSIPV VIHGSPTSIW
     VASMIIGIHN RLTSIHFKNY AT
//