ID   T1KHJ2_TETUR            Unreviewed;       543 AA.
AC   T1KHJ2;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   RecName: Full=Apyrase {ECO:0008006|Google:ProtNLM};
OS   Tetranychus urticae (Two-spotted spider mite).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Acariformes; Trombidiformes; Prostigmata; Eleutherengona; Raphignathae;
OC   Tetranychoidea; Tetranychidae; Tetranychus.
OX   NCBI_TaxID=32264 {ECO:0000313|EnsemblMetazoa:tetur11g04590.1, ECO:0000313|Proteomes:UP000015104};
RN   [1] {ECO:0000313|Proteomes:UP000015104}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=London {ECO:0000313|Proteomes:UP000015104};
RA   Rombauts S.;
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:tetur11g04590.1}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the GDA1/CD39 NTPase family.
CC       {ECO:0000256|ARBA:ARBA00009283}.
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DR   EMBL; CAEY01000075; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; T1KHJ2; -.
DR   STRING; 32264.T1KHJ2; -.
DR   EnsemblMetazoa; tetur11g04590.1; tetur11g04590.1; tetur11g04590.
DR   eggNOG; KOG1386; Eukaryota.
DR   HOGENOM; CLU_010246_6_0_1; -.
DR   OMA; WHDALFD; -.
DR   Proteomes; UP000015104; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   Gene3D; 3.30.420.40; -; 1.
DR   Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR   InterPro; IPR000407; GDA1_CD39_NTPase.
DR   PANTHER; PTHR11782; ADENOSINE/GUANOSINE DIPHOSPHATASE; 1.
DR   PANTHER; PTHR11782:SF121; NUCLEOSIDE-DIPHOSPHATASE MIG-23; 1.
DR   Pfam; PF01150; GDA1_CD39; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015104};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        484..504
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   ACT_SITE        101
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600407-1"
FT   BINDING         151..155
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600407-2"
SQ   SEQUENCE   543 AA;  61321 MW;  C18AFA919BC9C20C CRC64;
     MMKDKLGKDL YKKITPGLSS FSVNPQDAYN YIYPLLEFAN NNVPSFKHKE TPLYIFATAG
     MRLLSKESQD AILTNLRNRI KSNSSFSFNP ANVQVISGKE EGIYSWISVN YLLGRFDHSM
     TSGVAKSLVA INLGNGITTR PRTVGMLEMG GASVQIAFEI TSKYELEEIR RRRGVKSQEE
     MKDVLAQFNL GCYSHDSDHS YLLYVTTYLG LGANVAKDSY LNYILDQQLK YNKEPIVNNF
     KSLSNTTNQS YNNLPSSIGA EAVRINEPTP QPLITLKDPC LCKNCPLNRT VTSLNGSQYN
     LSLIGTGVFE HCEANLRNLI APKYEINPVC PVKNTTCPLK QLSETRVSFA DSEFFGFSEL
     WYSMEDVLGV GGKYNYFNFK KAAIDYCSTD YILLKERFSK NLYPNADSNR LYDQCFKAAW
     IATLLHDGFK MPKSFKNYQS ALSINNNQVQ WTLGALLYRI GIMSPSNAKE IQSHPAVVPD
     LSTFHNLLFL FCMTLVLAII VIYLKHLNYM INTSGKLSEM SIKTDLLRKV RPSDTIILID
     RNE
//