ID T1KVT6_TETUR Unreviewed; 1017 AA.
AC T1KVT6;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 2.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=Rho-GAP domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Tetranychus urticae (Two-spotted spider mite).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Eleutherengona; Raphignathae;
OC Tetranychoidea; Tetranychidae; Tetranychus.
OX NCBI_TaxID=32264 {ECO:0000313|EnsemblMetazoa:tetur23g01800.1, ECO:0000313|Proteomes:UP000015104};
RN [1] {ECO:0000313|Proteomes:UP000015104}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=London {ECO:0000313|Proteomes:UP000015104};
RA Rombauts S.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:tetur23g01800.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; CAEY01000614; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; T1KVT6; -.
DR STRING; 32264.T1KVT6; -.
DR EnsemblMetazoa; tetur23g01800.1; tetur23g01800.1; tetur23g01800.
DR eggNOG; KOG1453; Eukaryota.
DR HOGENOM; CLU_2545552_0_0_1; -.
DR Proteomes; UP000015104; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd20816; C1_GMIP-like; 1.
DR Gene3D; 3.30.60.20; -; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR002219; PE/DAG-bd.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR15228; SPERMATHECAL PHYSIOLOGY VARIANT; 1.
DR PANTHER; PTHR15228:SF25; SPERMATHECAL PHYSIOLOGY VARIANT; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00109; C1; 1.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|PROSITE-
KW ProRule:PRU01077}; Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000015104};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 39..324
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 438..484
FT /note="Phorbol-ester/DAG-type"
FT /evidence="ECO:0000259|PROSITE:PS50081"
FT DOMAIN 501..700
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 894..971
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 991..1017
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..27
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 894..936
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 946..971
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1017 AA; 113327 MW; FA6D7703788551F5 CRC64;
MGGVKSNGNN NDMTGFDSIS SSSPPELDDP EARSLLTPND CDNRFLHLPE GIDLALHRTK
LWSKYAKDLI NYIDKRTNLE ADHVRNLTKL AQSVKPILKE EKYLPLQSIY LQALDNDLDN
SCATLANCSL LMGHKFIEPL AARRAEHEKM RKQIKSEWNR ELKRTHEALS NLRKARMVYF
QRKQEYERLR ALSNLAPELS HSSEMQGSII GGPGAIVGGC YGGSDQASKC ERKKRIEEEA
CLRAQEAEII YRNAINEANA RTRSCEELKK NLLTRIRELI YQCDQTLKAV TIGYFECQHN
LLKPIVGQFG ALSDLTKLYE PASEYADYVQ HLPEFTEKLR KCNGSYGNYK FDPSINSMTS
IKEQPQRVNC NNKHHNLSNC PENGVDSVNK DHLKSSNNIG LPINSSGDEI DGVTNYSTVG
NGYECTSKSS TLPITAQSHH FRKLKTPSRC RHCDAYVCFQ GLECINCGLT CHTKCRIELT
TIKCSNRRMR GLSKKMTTFG VDLKSHGDEI PYIIVKCITE LDNRGIMVKG LYRVSGVKSK
VDKLCQFFES STDSIDIEDV HPNVIANVLK LYLRQLPEPL ITFKLYSEFI RIAKQYPSNA
DGNGPDSDDA SIAVQIINQF KQVTQNLPTV HYQTLAFLCH HLKRVADQSE VNNMPSSNLG
IVFGPTLLRS SEGDSLSSLV DTGHQARAVQ LLITYVDQIF GPSEKLTNSI YNEIDGNEPD
LVDKHFSQNE LKETNRTQIT LTLEGNNNLY DRGELNDKPQ SKNNRIISNN YSIKNIKNSN
NNNNTVTINN NNNNNNKNNN KINENDNNNV IGLNNGVDGK RSLDRERLSP TPSIYSSSAV
IKLSGQQIIT GPSSLIHSSL PNYDDSDDRL NRSNVIGGSR HSLYEARRQF FASPTSLTSS
SSLSSSPLST STSNSSIRPH SLVSGSISLN SQNHSTHHNH SHSHHQSIKQ TSSQPSSSTL
SSPATSPSNT NELQMAMSSL SLTRPRKASI ISNGPSLSLG TNNNDNSNNM FNTETNG
//
