ID T1L6G4_TETUR Unreviewed; 518 AA.
AC T1L6G4;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 2.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=EGF-like domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Tetranychus urticae (Two-spotted spider mite).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Eleutherengona; Raphignathae;
OC Tetranychoidea; Tetranychidae; Tetranychus.
OX NCBI_TaxID=32264 {ECO:0000313|EnsemblMetazoa:tetur79g00020.1, ECO:0000313|Proteomes:UP000015104};
RN [1] {ECO:0000313|Proteomes:UP000015104}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=London {ECO:0000313|Proteomes:UP000015104};
RA Rombauts S.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:tetur79g00020.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; CAEY01001863; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CAEY01001864; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; T1L6G4; -.
DR STRING; 32264.T1L6G4; -.
DR EnsemblMetazoa; tetur79g00020.1; tetur79g00020.1; tetur79g00020.
DR eggNOG; KOG1217; Eukaryota.
DR HOGENOM; CLU_604593_0_0_1; -.
DR Proteomes; UP000015104; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 5.
DR Gene3D; 6.20.200.20; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 6.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR024731; EGF_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR001007; VWF_dom.
DR PANTHER; PTHR24042:SF5; EGF_CA DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24042; NEL HOMOLOG; 1.
DR Pfam; PF12947; EGF_3; 1.
DR Pfam; PF07645; EGF_CA; 4.
DR Pfam; PF12661; hEGF; 1.
DR Pfam; PF00093; VWC; 1.
DR SMART; SM00181; EGF; 5.
DR SMART; SM00179; EGF_CA; 5.
DR SMART; SM00214; VWC; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR SUPFAM; SSF57603; FnI-like domain; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 4.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 4.
DR PROSITE; PS50026; EGF_3; 4.
DR PROSITE; PS01187; EGF_CA; 3.
DR PROSITE; PS50184; VWFC_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000015104};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 170..232
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 233..272
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 273..315
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 319..362
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 391..430
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT COILED 117..144
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 518 AA; 58289 MW; D8AE16B33475BFA0 CRC64;
MNFINLLYMQ NLSLTWFQIE LATCTLQVCN ENFMKAPSES IFELTHKLYS KVILLLVGVD
GTYWIGHSLK ERKLYFDFQI WRQEIRNQQI TGHINFTELP PLSSFCINLK VIFGESISEL
EDYVKNLTAQ LRETELRLSK VEDDRVKCPS LNCKSSYYLN DKDCCPVCHK KCLKDGKYIE
HGDVYIKDCV KCVCESGSLR CKRINPSTYC PPLNCPVDKQ FKKDGECCKY CLDYDFCGQG
HDCHPNASCH NLKTEYTCKC KSGFWGNGKD CHDVNECLEL GGINGHLCRD NSKCVNTNGS
YYCQCLPGFK RRDSLNCIDI NECESGGNHK CNENAACINT EGSYYCKCLP GYTGNGTHSI
CNKKCANGGK CIGPDKCSCR RGFYGNYCEK DIDECSLNIH HCPVNSECIN KPGWYYCQCL
SGYTNLDECN EGIDTCDENT ICVNTEGSYR CDCPSTISSS SQSQLQSLSS LSSSSSSSSC
SQDCVYLGQR RSHNETWESE IDSCSQCSCS SALLIVQN
//
