ID   T1PAQ9_MUSDO            Unreviewed;       413 AA.
AC   T1PAQ9;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Sec7 domain protein {ECO:0000313|EMBL:AFP60418.1};
OS   Musca domestica (House fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC   Muscidae; Musca.
OX   NCBI_TaxID=7370 {ECO:0000313|EMBL:AFP60418.1};
RN   [1] {ECO:0000313|EMBL:AFP60418.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ALHF {ECO:0000313|EMBL:AFP60418.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:AFP60418.1};
RA   Liu N., Zhang L., Li M., Reid W.;
RT   "Transcriptome of adult Musca domestica launches a platform for comparative
RT   house fly gene expression and characterization of differential gene
RT   expression among resistant and susceptible house flies.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KA645789; AFP60418.1; -; mRNA.
DR   AlphaFoldDB; T1PAQ9; -.
DR   VEuPathDB; VectorBase:MDOA009111; -.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR   CDD; cd01252; PH_GRP1-like; 1.
DR   CDD; cd00171; Sec7; 1.
DR   Gene3D; 1.10.220.20; -; 1.
DR   Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR023394; Sec7_C_sf.
DR   InterPro; IPR000904; Sec7_dom.
DR   InterPro; IPR035999; Sec7_dom_sf.
DR   PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR   PANTHER; PTHR10663:SF406; MIP16918P; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF01369; Sec7; 1.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00222; Sec7; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF48425; Sec7 domain; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS50190; SEC7; 1.
PE   2: Evidence at transcript level;
FT   DOMAIN          74..261
FT                   /note="SEC7"
FT                   /evidence="ECO:0000259|PROSITE:PS50190"
FT   DOMAIN          279..394
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          72..92
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   413 AA;  47989 MW;  CAFE9267D0BB7755 CRC64;
     MSISNGIGKS RNVKAGLYYN NNIGSLCDDC RTVIERNRNN RDMHQQPSML LRHKQIKDEL
     CEVVSEMEAL DVPEDSKHSN KDKQMSMGRK KFNMDPKKGI EHLVEHRLLR HDPQDVAHFL
     YKGEGLNKTA IGDYLGENND FNKEVLKAFV ALHDFTNLIL VQALRQFLWS FRLPGEAQKI
     DRMMECFAQR YCQLNPDIFT NTDTCYVLSF AIIMLNTSLH NPSVKDKPTV EQFISMNRGI
     NNGGDLPRTL LESLYESIRT EPFKIPQDDG NDLMHTFFNP DKEGWLWKQG GRYKSWKRRW
     FILNDNCLYY FEYTTDKEPR GIIPLENICV REIHDRSKPN CFELFATGGA EIIKACKTDS
     EGKVVEGKHS VYRMSAATEE DQQEWIKRLT QSISHNPFYD ILVQRKKKAL SKS
//