ID T1PLK0_MUSDO Unreviewed; 428 AA.
AC T1PLK0;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Adenylate cyclase associated (CAP) {ECO:0000313|EMBL:AFP64218.1};
DE SubName: Full=Adenylyl cyclase-associated protein 1 isoform X1 {ECO:0000313|RefSeq:XP_011294891.1};
GN Name=LOC101897595 {ECO:0000313|RefSeq:XP_011294891.1};
GN Synonyms=101897595 {ECO:0000313|EnsemblMetazoa:MDOA013575-PC};
OS Musca domestica (House fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Musca.
OX NCBI_TaxID=7370 {ECO:0000313|EMBL:AFP64218.1};
RN [1] {ECO:0000313|EMBL:AFP64218.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ALHF {ECO:0000313|EMBL:AFP64218.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:AFP64218.1};
RA Liu N., Zhang L., Li M., Reid W.;
RT "Transcriptome of adult Musca domestica launches a platform for comparative
RT house fly gene expression and characterization of differential gene
RT expression among resistant and susceptible house flies.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:MDOA013575-PC}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|EnsemblMetazoa:MDOA013575-PC};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
RN [3] {ECO:0000313|RefSeq:XP_011294891.1}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|RefSeq:XP_011294891.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CAP family. {ECO:0000256|ARBA:ARBA00007659}.
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DR EMBL; KA649589; AFP64218.1; -; mRNA.
DR RefSeq; XP_011294891.1; XM_011296589.2.
DR EnsemblMetazoa; MDOA013575-RC; MDOA013575-PC; MDOA013575.
DR VEuPathDB; VectorBase:MDOA013575; -.
DR OrthoDB; 1453907at2759; -.
DR Proteomes; UP000095301; Unassembled WGS sequence.
DR Proteomes; UP000694905; Unplaced.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR Gene3D; 2.160.20.70; -; 1.
DR Gene3D; 1.25.40.330; Adenylate cyclase-associated CAP, N-terminal domain; 1.
DR InterPro; IPR001837; Adenylate_cyclase-assoc_CAP.
DR InterPro; IPR013912; Adenylate_cyclase-assoc_CAP_C.
DR InterPro; IPR017901; C-CAP_CF_C-like.
DR InterPro; IPR016098; CAP/MinC_C.
DR InterPro; IPR036223; CAP_C_sf.
DR InterPro; IPR028417; CAP_CS_C.
DR InterPro; IPR036222; CAP_N_sf.
DR InterPro; IPR006599; CARP_motif.
DR InterPro; IPR003124; WH2_dom.
DR PANTHER; PTHR10652; ADENYLYL CYCLASE-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR10652:SF0; ADENYLYL CYCLASE-ASSOCIATED PROTEIN; 1.
DR Pfam; PF08603; CAP_C; 1.
DR SMART; SM00673; CARP; 2.
DR SUPFAM; SSF69340; C-terminal domain of adenylylcyclase associated protein; 1.
DR SUPFAM; SSF101278; N-terminal domain of adenylylcyclase associated protein, CAP; 1.
DR PROSITE; PS51329; C_CAP_COFACTOR_C; 1.
DR PROSITE; PS01089; CAP_2; 1.
DR PROSITE; PS51082; WH2; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000694905}.
FT DOMAIN 209..230
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT DOMAIN 271..406
FT /note="C-CAP/cofactor C-like"
FT /evidence="ECO:0000259|PROSITE:PS51329"
SQ SEQUENCE 428 AA; 46624 MW; 2BE880CDD5BCE0EE CRC64;
MSVLGYQDII NGPLSQYLAL SAKIGGDVAK HADFVKKAFD AQLQYVTLAT QCSKPDQNKQ
MELLKPTSDQ ITAIQDFREK NRASPFFNHL SAISESIPAL GWVCVSPTPG PHVKEMNDAG
QFYTNRVLKE WKEKDATHVE WARAWVQTLT ELQQYIKQNH TTGLVWSGKG AAPASGAVPP
PPPMGGCPPP PPPPTFDMSN MSLEGGADER SALFAEINQG ENITKNLKKV TADMQTHKNP
TLRTGPAPFK APTTQLGSAV SKGPVVEVAK PPVFTRDGKK WLIEYQKNNP NLLVENAEMN
NVVYVFRCEG STLTVKGKVN NVVFDSCKKC SLLFDSVVAS VEFVNCQSVQ MQVLGNVPTI
SIDKTDGCQM YLSKDSLGVE IVSSKSSEMN VMLPADDNGD YTELPLPEQF KTTISGKALK
TVCVDSLG
//
