ID   T1XBI8_VARPD            Unreviewed;       315 AA.
AC   T1XBI8;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Putative adenylate/guanylate cyclase {ECO:0000313|EMBL:AGU49851.1};
GN   ORFNames=VAPA_1c27540 {ECO:0000313|EMBL:AGU49851.1};
OS   Variovorax paradoxus B4.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Variovorax.
OX   NCBI_TaxID=1246301 {ECO:0000313|EMBL:AGU49851.1, ECO:0000313|Proteomes:UP000016223};
RN   [1] {ECO:0000313|EMBL:AGU49851.1, ECO:0000313|Proteomes:UP000016223}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B4 {ECO:0000313|EMBL:AGU49851.1,
RC   ECO:0000313|Proteomes:UP000016223};
RA   Schuldes J., Brandt U., Hiessl S., Wuebbeler J.H., Thuermer A.,
RA   Steinbuechel A., Daniel R.;
RT   "Genome sequence of Variovorax paradoxus B4.";
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP003911; AGU49851.1; -; Genomic_DNA.
DR   RefSeq; WP_021007344.1; NC_022247.1.
DR   AlphaFoldDB; T1XBI8; -.
DR   KEGG; vpd:VAPA_1c27540; -.
DR   PATRIC; fig|1246301.3.peg.2788; -.
DR   HOGENOM; CLU_080930_0_0_4; -.
DR   OrthoDB; 9801841at2; -.
DR   Proteomes; UP000016223; Chromosome 1.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   CDD; cd00060; FHA; 1.
DR   Gene3D; 2.60.200.20; -; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR000253; FHA_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   Pfam; PF00498; FHA; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM00240; FHA; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR   PROSITE; PS50006; FHA_DOMAIN; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
FT   DOMAIN          6..121
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   DOMAIN          213..256
FT                   /note="FHA"
FT                   /evidence="ECO:0000259|PROSITE:PS50006"
SQ   SEQUENCE   315 AA;  34320 MW;  EE82376530081ED3 CRC64;
     MDVNSTVVFA DLTGSSRVFE AMGNARATDT VTRLTQWIGS VCQAHGGRVV KSLGDGVFAI
     FSNAATAMPA VIELQRYHQK RLMTWPVPLR MALQIGVASG EVVEVEGDCF GDAVNLASRL
     SDLAGPGQIW ATDAAIAQLS EIGVRHRDLG LITIRGRSEM SAVHRIDWQD EMTSFLTLPA
     ALTPLRLPDS SLGQIELAWL DVRSVFRIEE LPIHLGRVHD AQFVVNDPRV SRLHARIELR
     HGSCVLTDLS TYGTWVRFHG NGGPSHEVAL RREECVLHGR GEIGLGAPLS DFTAPTIAFN
     TAGAEVQLSR REITN
//