ID T1XK54_VARPD Unreviewed; 863 AA.
AC T1XK54;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Calcium-transporting ATPase {ECO:0000313|EMBL:AGU52963.1};
DE EC=3.6.3.8 {ECO:0000313|EMBL:AGU52963.1};
GN ORFNames=VAPA_2c04030 {ECO:0000313|EMBL:AGU52963.1};
OS Variovorax paradoxus B4.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Variovorax.
OX NCBI_TaxID=1246301 {ECO:0000313|EMBL:AGU52963.1, ECO:0000313|Proteomes:UP000016223};
RN [1] {ECO:0000313|EMBL:AGU52963.1, ECO:0000313|Proteomes:UP000016223}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B4 {ECO:0000313|EMBL:AGU52963.1,
RC ECO:0000313|Proteomes:UP000016223};
RA Schuldes J., Brandt U., Hiessl S., Wuebbeler J.H., Thuermer A.,
RA Steinbuechel A., Daniel R.;
RT "Genome sequence of Variovorax paradoxus B4.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP003912; AGU52963.1; -; Genomic_DNA.
DR RefSeq; WP_021003792.1; NC_022234.1.
DR AlphaFoldDB; T1XK54; -.
DR KEGG; vpd:VAPA_2c04030; -.
DR PATRIC; fig|1246301.3.peg.5925; -.
DR HOGENOM; CLU_002360_2_1_4; -.
DR OrthoDB; 9814270at2; -.
DR Proteomes; UP000016223; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0015662; F:P-type ion transporter activity; IEA:UniProt.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR004014; ATPase_P-typ_cation-transptr_N.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR42861; CALCIUM-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR42861:SF156; CALCIUM-TRANSPORTING ATPASE; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00690; Cation_ATPase_N; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00120; HATPASE.
DR SFLD; SFLDG00002; C1.7:_P-type_atpase_like; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000313|EMBL:AGU52963.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 64..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 637..658
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 664..684
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 705..725
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 745..762
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 783..803
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 809..831
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..52
FT /note="Cation-transporting P-type ATPase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00690"
FT DOMAIN 661..836
FT /note="Cation-transporting P-type ATPase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00689"
SQ SEQUENCE 863 AA; 91807 MW; CCD6064DFAC4AD3B CRC64;
MADPCDLTDA VARQRLAQDG PNEVTVSRPR SVLRLAREVA SEPMFLLLAA CGSIYLALGD
AQEALMLLGF VFIVMGLSFV QQRRSERSLE ALRDLSSPQA LVRRGGAMRR IAARELVVGD
MVLLSEGDRV PADMSLLDAS NLAIDESLLT GESVPVTKRA LASEEAMAAD AWTAFSGTLV
TQGTARGRVT ATGARSALGR IGASLAGIAA QATPIQRETR GVVKGVAIGG LALAAALAAA
YGALRGDWLQ GLLAGLTLAM GIIPEELPMV LALFLGLGAW RLVREKVLAR SIPAVELLGA
TTVLCVDKTG TLTANRMSVR QLRSGDARYD ALETKGAALQ EELHPLLEYA VLASHRRTFD
PMESAIAEAA GQWLAGTEHL HSDWTLIDDY PLSPELLAMS RVWRSPDQRA FLIAAKGAPE
AIVDLCHMDA GRAGRIAEQV LEMATDGLRV LGVACGTFDA DVLPGLQHDF DFRFLGLVGL
EDPVRADVPQ AIAECRAAGI RVVMMTGDHP ATAIAVARQA GLSAEAPVMT GVEMASLADE
ALAARLAATT IFCRVQPDQK LRLVRAFRAQ GDVVAMTGDG VNDAPALKAA DIGVAMGARG
TEVAREAAAL VLLNDDFASL VTAIRHGRRV FANLRKAIVF VVAVHVPIVG LSILPVVFGW
PLLLMPVHIL FLQLIIDPAC SVVFEAEPLE ESAMKVPPRR PDQRLFDSAV LVRGLWQGGV
LLGMLLVTYA GARWMASLEA GRDDMARTLT FVVLVLSNLG LIQSNRSWER TAWHGNTASN
RQFGWIAAGA VAVLCAVLTV PAVGRLFSFV MPSPLLLAAG LGMAVLSMLW FECIKWGLRR
KVRGNASPGG AVHLPANSCS SRR
//
