ID   T2DLA8_ALTMD            Unreviewed;       539 AA.
AC   T2DLA8;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:AGV53622.1};
GN   ORFNames=MADE_000001020780 {ECO:0000313|EMBL:AGV53622.1};
OS   Alteromonas mediterranea (strain DSM 17117 / CIP 110805 / LMG 28347 / Deep
OS   ecotype).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC   Alteromonadaceae; Alteromonas/Salinimonas group; Alteromonas.
OX   NCBI_TaxID=1774373 {ECO:0000313|EMBL:AGV53622.1, ECO:0000313|Proteomes:UP000001870};
RN   [1] {ECO:0000313|EMBL:AGV53622.1, ECO:0000313|Proteomes:UP000001870}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17117 / CIP 110805 / LMG 28347 / Deep ecotype
RC   {ECO:0000313|Proteomes:UP000001870};
RX   PubMed=18670397; DOI=10.1038/ismej.2008.74;
RA   Ivars-Martinez E., Martin-Cuadrado A.B., D'Auria G., Mira A., Ferriera S.,
RA   Johnson J., Friedman R., Rodriguez-Valera F.;
RT   "Comparative genomics of two ecotypes of the marine planktonic copiotroph
RT   Alteromonas macleodii suggests alternative lifestyles associated with
RT   different kinds of particulate organic matter.";
RL   ISME J. 2:1194-1212(2008).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP001103; AGV53622.1; -; Genomic_DNA.
DR   RefSeq; WP_023559516.1; NC_011138.3.
DR   AlphaFoldDB; T2DLA8; -.
DR   KEGG; amc:MADE_000001020780; -.
DR   HOGENOM; CLU_000445_107_27_6; -.
DR   Proteomes; UP000001870; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR000727; T_SNARE_dom.
DR   PANTHER; PTHR32089:SF112; HEME-BASED AEROTACTIC TRANSDUCER HEMAT; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS50192; T_SNARE; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Methylation {ECO:0000256|ARBA:ARBA00022481};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        184..207
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          208..262
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          267..503
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   DOMAIN          454..516
FT                   /note="T-SNARE coiled-coil homology"
FT                   /evidence="ECO:0000259|PROSITE:PS50192"
SQ   SEQUENCE   539 AA;  58036 MW;  91B5BF84BA4E9352 CRC64;
     MNFLKKMSIA SKIFLIPGIA AISFVIYLLI TVYTALNNGA TLEKVQQVQF PALQQSASTL
     VDMQKVRDTL SSAVTTGDQD TLIMAQNLAK EVKAGLNQIG SISPEFRTEI AKISAGFDDY
     FKVAFDVSQS MVDGTADFSR LGELSSQMNS SYDDAIAAMS TFSDAQQAAF EEAFENTDRA
     NTSLISTGVI LAIVVTILLF ATAVPIVRGI KQSIDDVVRS LKDIAQENGD LTVRIETKSE
     DEIGELVYWF NQFMDKLQGV VRDVVEASLP LSNLAQNLRG VTEETQRTIN VQQQSATNAK
     SAVDTMSGSV DGVAHSAAQA ASDANEATSA ASEGRQIVQQ TVTSIQQLAE NVRETADVIA
     RLESDSNKVG SVLDVIKGIA EQTNLLALNA AIEAARAGEQ GRGFAVVADE VRTLASRTQQ
     STEEIQSTIE QLQSAAHSAV EVMARGTEQA SSSVETANKA GSSLETITST IGRINQMNEQ
     IAHNTEDQRT VAVDIVRHVD EIHQRTEQTS SRSVELGTMC NELADLAQHL ESIAKQFRV
//