ID T2HS89_ECOLX Unreviewed; 187 AA.
AC T2HS89;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Adenine-specific DNA methylase {ECO:0000313|EMBL:BAN82855.1};
DE SubName: Full=SAM-dependent methyltransferase {ECO:0000313|EMBL:EFA8787296.1, ECO:0000313|EMBL:OKV07642.1};
GN ORFNames=AWP47_19210 {ECO:0000313|EMBL:OKV07642.1}, C2R31_005271
GN {ECO:0000313|EMBL:EFA8787296.1}, CR628_005216
GN {ECO:0000313|EMBL:EFC8022934.1}, NCTC8179_07101
GN {ECO:0000313|EMBL:STO41485.1}, NCTC8622_00114
GN {ECO:0000313|EMBL:STI81190.1};
OS Escherichia coli.
OG Plasmid pCss165Kan {ECO:0000313|EMBL:BAN82855.1}.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=562 {ECO:0000313|EMBL:BAN82855.1};
RN [1] {ECO:0000313|EMBL:BAN82855.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=4266 delta cssB::Km {ECO:0000313|EMBL:BAN82855.1};
RC PLASMID=pCss165Kan {ECO:0000313|EMBL:BAN82855.1};
RX PubMed=23933356; DOI=10.1016/j.plasmid.2013.07.006;
RA Wajima T., Sabui S., Kano S., Ramamurthy T., Chatterjee N.S., Hamabata T.;
RT "Entire sequence of the colonization factor coli surface antigen 6-encoding
RT plasmid pCss165 from an enterotoxigenic Escherichia coli clinical
RT isolate.";
RL Plasmid 70:343-352(2013).
RN [2] {ECO:0000313|EMBL:OKV07642.1, ECO:0000313|Proteomes:UP000185794}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=700324 {ECO:0000313|EMBL:OKV07642.1,
RC ECO:0000313|Proteomes:UP000185794};
RA Del Canto F., Vidal R., Stine O.C., Pop M.;
RT "Chaperone-usher pili loci of human colonization factor-negative
RT enterotoxigenic Escherichia coli.";
RL Front. Cell. Infect. Microbiol. 0:0-0(2017).
RN [3] {ECO:0000313|Proteomes:UP000254079, ECO:0000313|Proteomes:UP000255543}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC8179 {ECO:0000313|EMBL:STO41485.1,
RC ECO:0000313|Proteomes:UP000255543}, and NCTC8622
RC {ECO:0000313|EMBL:STI81190.1, ECO:0000313|Proteomes:UP000254079};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|Proteomes:UP000518092, ECO:0000313|Proteomes:UP000567387}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2017EL-1017b {ECO:0000313|EMBL:EFC8022934.1,
RC ECO:0000313|Proteomes:UP000518092}, and PNUSAE011918
RC {ECO:0000313|EMBL:EFA8787296.1, ECO:0000313|Proteomes:UP000567387};
RG PulseNet: The National Subtyping Network for Foodborne Disease Surveillance;
RA Tarr C.L., Trees E., Katz L.S., Carleton-Romer H.A., Stroika S.,
RA Kucerova Z., Roache K.F., Sabol A.L., Besser J., Gerner-Smidt P.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AB702969; BAN82855.1; -; Genomic_DNA.
DR EMBL; AASCBU010000072; EFA8787296.1; -; Genomic_DNA.
DR EMBL; AASIMK010000134; EFC8022934.1; -; Genomic_DNA.
DR EMBL; LRKC01000146; OKV07642.1; -; Genomic_DNA.
DR EMBL; UGCP01000001; STI81190.1; -; Genomic_DNA.
DR EMBL; UGEB01000005; STO41485.1; -; Genomic_DNA.
DR RefSeq; WP_001297832.1; NZ_WNIN01000018.1.
DR RefSeq; YP_008531386.1; NC_022333.1.
DR PATRIC; fig|562.7076.peg.5180; -.
DR Proteomes; UP000185794; Unassembled WGS sequence.
DR Proteomes; UP000254079; Unassembled WGS sequence.
DR Proteomes; UP000255543; Unassembled WGS sequence.
DR Proteomes; UP000518092; Unassembled WGS sequence.
DR Proteomes; UP000567387; Unassembled WGS sequence.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:UniProt.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:UniProt.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR007848; Small_mtfrase_dom.
DR Pfam; PF05175; MTS; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:BAN82855.1};
KW Plasmid {ECO:0000313|EMBL:BAN82855.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:OKV07642.1}.
FT DOMAIN 50..149
FT /note="Methyltransferase small"
FT /evidence="ECO:0000259|Pfam:PF05175"
SQ SEQUENCE 187 AA; 21142 MW; 46690AF6C2DA2DBB CRC64;
MHSQLRERIR LLRARLDNAA PVAEIRAESQ LFVTPAPVCD RLVTLAEISN RDHILEPSAG
TGAILRAIRD TAPEAMCDAV ESNSGLVRYL RENFNGVRVQ CGDFMEWQPV QYYSRIIMNP
PFSHGQDIRH ILRAFSLLRP GGVLVAVCLN GPRQQEKLLP FSDIREELPR GTFAYTHVPT
MIIRLRA
//
