ID T2JNX3_CROWT Unreviewed; 476 AA.
AC T2JNX3;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Potassium efflux system KefA protein / Small-conductance mechanosensitive channel {ECO:0000313|EMBL:CCQ66739.1};
GN ORFNames=CWATWH0402_874 {ECO:0000313|EMBL:CCQ66739.1};
OS Crocosphaera watsonii WH 0402.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Chroococcales; Aphanothecaceae; Crocosphaera.
OX NCBI_TaxID=1284629 {ECO:0000313|EMBL:CCQ66739.1, ECO:0000313|Proteomes:UP000018130};
RN [1] {ECO:0000313|EMBL:CCQ66739.1, ECO:0000313|Proteomes:UP000018130}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WH 0402 {ECO:0000313|EMBL:CCQ66739.1,
RC ECO:0000313|Proteomes:UP000018130};
RA Bench S.;
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CCQ66739.1, ECO:0000313|Proteomes:UP000018130}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WH 0402 {ECO:0000313|EMBL:CCQ66739.1,
RC ECO:0000313|Proteomes:UP000018130};
RA Bench S.R., Heller P., Frank I., Arciniega M., Shilova I.N., Zehr J.P.;
RT "Whole genome comparison of six Crocosphaera watsonii strains with
RT differing phenotypes.";
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCQ66739.1}.
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DR EMBL; CAQN01000469; CCQ66739.1; -; Genomic_DNA.
DR RefSeq; WP_007308791.1; NZ_CAQN01000469.1.
DR AlphaFoldDB; T2JNX3; -.
DR Proteomes; UP000018130; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR30347:SF1; MINICONDUCTANCE MECHANOSENSITIVE CHANNEL MSCM; 1.
DR PANTHER; PTHR30347; POTASSIUM CHANNEL RELATED; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 30..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 317..436
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
SQ SEQUENCE 476 AA; 54140 MW; 9E06791E3D09887D CRC64;
MSTYWSIIQQ WFNETFSTPL FNIGGEKISI LWILKAIMLL IFVSILARGV KRFLKNYLLV
LLRIDEGTRE VVGTLSSLGL GTLGCIIVLQ GLGLDLASFA VVVGGLGVGI GFGLQEITRN
LVSGLTLLGE SKLKVGDLIE FQGHLGYIQE ISLRSTVIKT FEGSQLVIPN TDLTSQPVEN
WNYENCQGRI EISIGVAYNS DLLLVTELLL EAAFLEQEVL PNPSPKVVFV EYGDNALIFE
LWVWVANIEN RKFIKSSLNF IIEYKFRQGG ISIPFPQREL WVKNVESLQL NTLQNIPDKS
PISHHITLKD SLKSFPCFQH LDELELRKLI EAGSRRHLKK DEIFINRGEY DSHFCIVLLG
QIQAIYETKK VSRLLFTFNQ GDYFGELPLL LEIPYPTTMS ASEDTQLFLL GKTCFQNLLD
QYPYLEKEIA TELVKRQEAL EEHQNSLKEM GLIDDEYLKN PVVWIRKRLS QIFNLS
//
