ID   T2M595_HYDVU            Unreviewed;       673 AA.
AC   T2M595;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Intraflagellar transport protein 122 homolog {ECO:0000256|ARBA:ARBA00019442};
DE   Flags: Fragment;
GN   Name=IFT122 {ECO:0000313|EMBL:CDG67236.1};
OS   Hydra vulgaris (Hydra) (Hydra attenuata).
OC   Eukaryota; Metazoa; Cnidaria; Hydrozoa; Hydroidolina; Anthoathecata;
OC   Aplanulata; Hydridae; Hydra.
OX   NCBI_TaxID=6087 {ECO:0000313|EMBL:CDG67236.1};
RN   [1] {ECO:0000313|EMBL:CDG67236.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Whole animals {ECO:0000313|EMBL:CDG67236.1};
RX   PubMed=24065732; DOI=10.1093/gbe/evt142;
RA   Wenger Y., Galliot B.;
RT   "Punctuated emergences of genetic and phenotypic innovations in eumetazoan,
RT   bilaterian, euteleostome, and hominidae ancestors.";
RL   Genome Biol. Evol. 5:1949-1968(2013).
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DR   EMBL; HAAD01001004; CDG67236.1; -; mRNA.
DR   AlphaFoldDB; T2M595; -.
DR   GO; GO:0031514; C:motile cilium; IEA:UniProtKB-KW.
DR   GO; GO:0060271; P:cilium assembly; IEA:InterPro.
DR   Gene3D; 1.25.40.470; -; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR039857; Ift122/121.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR12764:SF4; INTRAFLAGELLAR TRANSPORT PROTEIN 122 HOMOLOG; 1.
DR   PANTHER; PTHR12764; WD REPEAT DOMAIN-RELATED; 1.
DR   Pfam; PF13176; TPR_7; 1.
DR   Pfam; PF00400; WD40; 1.
DR   SMART; SM00320; WD40; 2.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
PE   2: Evidence at transcript level;
KW   Cell projection {ECO:0000313|EMBL:CDG67236.1};
KW   Cilium {ECO:0000313|EMBL:CDG67236.1};
KW   Flagellum {ECO:0000313|EMBL:CDG67236.1};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CDG67236.1"
SQ   SEQUENCE   673 AA;  77302 MW;  CBD56C8E81E49A17 CRC64;
     KGEFLIVSGS DKKCYLYTKE GTRLAIIGEH EGWVWSCKIG PEGNYVACGS EDGTVAYYQL
     IFSTVHGLYK DRYAYRDNMT DVIVHHLTTE QKVRIKCREL VKKIAIYKHR LAVQMPEKIV
     IYEIYSNDSA DMTYKVKDRI NQKVECNLLV VTGNNLILCQ ERRLQCLSFD GIKEREWQVD
     SVIRYIKIAG GVSGHEGLLV GLKNGQILKI FVDNQFPIPL IKQQTGVRCL DISCSHKKLA
     VVDDNNTILV YQIDTKELLF QEANGNSVAW NTHNDDMLCF SGGGMLNIKA GNFPLHQQKV
     PGFVVGFCGS RIYCLHVYTM TSIEVPQSTP MYQFLEKKLF LDAYKIACLG VTDGDWRTLA
     MSALESLELE VAKLSFIRIR DMKFLELINT IEARKKRGEN DNNTFLGDIY AYQGKFQEAA
     KLYKRAGKEE KALEMFSDLR QFEQAKEFLG SSDQNNFKQL IKKQAEWCRT TNDPKAAADM
     FIAAGEFMKA IDILGENGWF EKLLELARNL NKADVEPLTA CAQHLANMKK YNYAAEVYLK
     MGDKKKLVQL YVQSHQWDEV FHLVEKHVEF KDDVYVPYAH WLAENDRFDE AQEAFHKAGR
     RTDAVKVLEQ LTLNAVIENR FNDAGYYFWQ LSMQCLDIAG KKESGELKEV EDSILDKFVE
     YQTKAEVYYV YHL
//