ID T2M5L2_HYDVU Unreviewed; 377 AA.
AC T2M5L2;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=ethanolamine kinase {ECO:0000256|ARBA:ARBA00038874};
DE EC=2.7.1.82 {ECO:0000256|ARBA:ARBA00038874};
GN Name=ETNK1 {ECO:0000313|EMBL:CDG67227.1};
GN Synonyms=LOC100201708 {ECO:0000313|RefSeq:XP_002167496.2,
GN ECO:0000313|RefSeq:XP_012560529.1, ECO:0000313|RefSeq:XP_012560530.1};
OS Hydra vulgaris (Hydra) (Hydra attenuata).
OC Eukaryota; Metazoa; Cnidaria; Hydrozoa; Hydroidolina; Anthoathecata;
OC Aplanulata; Hydridae; Hydra.
OX NCBI_TaxID=6087 {ECO:0000313|EMBL:CDG67227.1};
RN [1] {ECO:0000313|EMBL:CDG67227.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Whole animals {ECO:0000313|EMBL:CDG67227.1};
RX PubMed=24065732; DOI=10.1093/gbe/evt142;
RA Wenger Y., Galliot B.;
RT "Punctuated emergences of genetic and phenotypic innovations in eumetazoan,
RT bilaterian, euteleostome, and hominidae ancestors.";
RL Genome Biol. Evol. 5:1949-1968(2013).
RN [2] {ECO:0000313|RefSeq:XP_002167496.2, ECO:0000313|RefSeq:XP_012560529.1}
RP IDENTIFICATION.
RC STRAIN=105 {ECO:0000313|RefSeq:XP_002167496.2,
RC ECO:0000313|RefSeq:XP_012560529.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Phospholipid metabolism; phosphatidylethanolamine
CC biosynthesis; phosphatidylethanolamine from ethanolamine: step 1/3.
CC {ECO:0000256|ARBA:ARBA00037883}.
CC -!- SIMILARITY: Belongs to the choline/ethanolamine kinase family.
CC {ECO:0000256|ARBA:ARBA00038211}.
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DR EMBL; HAAD01000995; CDG67227.1; -; mRNA.
DR RefSeq; XP_002167496.2; XM_002167460.3.
DR RefSeq; XP_012560529.1; XM_012705075.1.
DR RefSeq; XP_012560530.1; XM_012705076.1.
DR EnsemblMetazoa; XM_002167460.3; XP_002167496.2; LOC100201708.
DR EnsemblMetazoa; XM_002167460.4; XP_002167496.2; LOC100201708.
DR EnsemblMetazoa; XM_012705075.1; XP_012560529.1; LOC100201708.
DR EnsemblMetazoa; XM_012705075.2; XP_012560529.1; LOC100201708.
DR EnsemblMetazoa; XM_012705076.1; XP_012560530.1; LOC100201708.
DR EnsemblMetazoa; XM_012705076.2; XP_012560530.1; LOC100201708.
DR EnsemblMetazoa; XM_047278780.1; XP_047134736.1; LOC100201708.
DR GeneID; 100201708; -.
DR KEGG; hmg:100201708; -.
DR OMA; HNDLIPR; -.
DR OrthoDB; 144299at2759; -.
DR Proteomes; UP000694840; Unplaced.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05157; ETNK_euk; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR22603; CHOLINE/ETHANOALAMINE KINASE; 1.
DR PANTHER; PTHR22603:SF66; ETHANOLAMINE KINASE; 1.
DR Pfam; PF01633; Choline_kinase; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 2: Evidence at transcript level;
KW Kinase {ECO:0000313|EMBL:CDG67227.1, ECO:0000313|RefSeq:XP_002167496.2};
KW Reference proteome {ECO:0000313|Proteomes:UP000694840};
KW Transferase {ECO:0000313|EMBL:CDG67227.1,
KW ECO:0000313|RefSeq:XP_002167496.2}.
SQ SEQUENCE 377 AA; 44183 MW; E71837693CF895A3 CRC64;
MASSYINRLN DIPHFEVKIT EKNVETTVQL LISHLKKSWN INKLNKKVYD SGITNKLYGY
YVNYDGTIVS PQFSEYGRSE IVLVRIYGNK TDLVIDRAQE LRNFEELSRC GIAPSIYCTF
SNGYCYKYME GRALNPKDFS DKNILNLCAR QVANIHCLQL SENYLKHYKL ESVLFKTINR
YISLIPHKYN SEEMQKKYLE LIPSIECLHS EVNQIISIVA NMKTKIVFCH NDLLCGNFIF
DEYNDKVVLI DYEYAGPNYA AYDIANHFNE YAGIEDFDFS LYPSKEAQME WLNIYMIETN
KIKGLTVEVS EKELECLYSQ VQVFSLVSHL FWGIWALIQA HYSDINFDFL WYSSMRLNEY
FKHKDAFLTI GKNAEFI
//
