ID T2M7E1_HYDVU Unreviewed; 531 AA.
AC T2M7E1;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Gamma-tubulin complex component {ECO:0000256|RuleBase:RU363050};
DE Flags: Fragment;
GN Name=TUBGCP5 {ECO:0000313|EMBL:CDG67877.1};
OS Hydra vulgaris (Hydra) (Hydra attenuata).
OC Eukaryota; Metazoa; Cnidaria; Hydrozoa; Hydroidolina; Anthoathecata;
OC Aplanulata; Hydridae; Hydra.
OX NCBI_TaxID=6087 {ECO:0000313|EMBL:CDG67877.1};
RN [1] {ECO:0000313|EMBL:CDG67877.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Whole animals {ECO:0000313|EMBL:CDG67877.1};
RX PubMed=24065732; DOI=10.1093/gbe/evt142;
RA Wenger Y., Galliot B.;
RT "Punctuated emergences of genetic and phenotypic innovations in eumetazoan,
RT bilaterian, euteleostome, and hominidae ancestors.";
RL Genome Biol. Evol. 5:1949-1968(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center {ECO:0000256|RuleBase:RU363050}.
CC -!- SIMILARITY: Belongs to the TUBGCP family.
CC {ECO:0000256|ARBA:ARBA00010337, ECO:0000256|RuleBase:RU363050}.
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DR EMBL; HAAD01001645; CDG67877.1; -; mRNA.
DR AlphaFoldDB; T2M7E1; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
DR GO; GO:0000922; C:spindle pole; IEA:InterPro.
DR GO; GO:0043015; F:gamma-tubulin binding; IEA:InterPro.
DR GO; GO:0007020; P:microtubule nucleation; IEA:InterPro.
DR Gene3D; 1.20.120.1900; Gamma-tubulin complex, C-terminal domain; 1.
DR InterPro; IPR007259; GCP.
DR InterPro; IPR040457; GCP_C.
DR InterPro; IPR042241; GCP_C_sf.
DR InterPro; IPR041470; GCP_N.
DR PANTHER; PTHR19302; GAMMA TUBULIN COMPLEX PROTEIN; 1.
DR PANTHER; PTHR19302:SF33; GAMMA-TUBULIN COMPLEX COMPONENT 5; 1.
DR Pfam; PF04130; GCP_C_terminal; 1.
DR Pfam; PF17681; GCP_N_terminal; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|RuleBase:RU363050};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212,
KW ECO:0000256|RuleBase:RU363050};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701, ECO:0000256|RuleBase:RU363050}.
FT DOMAIN 9..92
FT /note="Gamma tubulin complex component protein N-terminal"
FT /evidence="ECO:0000259|Pfam:PF17681"
FT DOMAIN 213..518
FT /note="Gamma tubulin complex component C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04130"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CDG67877.1"
SQ SEQUENCE 531 AA; 62123 MW; F7FE1450EB95CC8B CRC64;
IGKLPHNSDE EFMICSLQAS KIVEKDEENY WRATYQIKET KSTNGNVKSL VPKFIEGIQQ
QILVTGKSLG LLAEFGDFSS LVVETSLHEE FRINLIKELQ QANDRFLKGD DGQVTGDITD
GSSIGFEDPL VDHLVQQNFN LMFGHAKQRC ITKKYIKNNQ RNEGESWSEL LKNGACRPPI
KLLIQKSLFP GILKRYDRVC KLLLDLFKEE FCLHQHFQVM KNFFLMEDGG TMHEFCIELF
QKAKEKTHWQ DKPFLNIVLQ DALQRRHLHL IGSLSVELQP HFIAASNSDI FDGMSLHYKA
PWPVTIILNA EAEQKYNEIF RFLLKVKRTM WTLEQLKFQE LINEPSMSQS HPTIGDTFDI
ELTCKFKKDD SVLEPIKQKL KLRMLIFRMK MMHVIRNFHF YLVSRIQNTT CAEFDAKLKE
TKDLDKVLEH HETFLLNLKQ RCLLREKIGR SRDAIFRILS LVFDFESLWM RGLVHLDENK
LNSLEIDFNR CAAFLHSFFN SLAKRGSYPH FEFLANALKI EAHGHQYVFR R
//
