ID T2MH01_HYDVU Unreviewed; 327 AA.
AC T2MH01;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Myc proto-oncogene protein {ECO:0000313|EMBL:CDG71543.1, ECO:0000313|RefSeq:XP_012554248.1};
GN Name=MYC {ECO:0000313|EMBL:CDG71543.1};
GN Synonyms=myc2 {ECO:0000313|RefSeq:XP_012554248.1};
OS Hydra vulgaris (Hydra) (Hydra attenuata).
OC Eukaryota; Metazoa; Cnidaria; Hydrozoa; Hydroidolina; Anthoathecata;
OC Aplanulata; Hydridae; Hydra.
OX NCBI_TaxID=6087 {ECO:0000313|EMBL:CDG71543.1};
RN [1] {ECO:0000313|EMBL:CDG71543.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Whole animals {ECO:0000313|EMBL:CDG71543.1};
RX PubMed=24065732; DOI=10.1093/gbe/evt142;
RA Wenger Y., Galliot B.;
RT "Punctuated emergences of genetic and phenotypic innovations in eumetazoan,
RT bilaterian, euteleostome, and hominidae ancestors.";
RL Genome Biol. Evol. 5:1949-1968(2013).
RN [2] {ECO:0000313|RefSeq:XP_012554248.1}
RP IDENTIFICATION.
RC STRAIN=105 {ECO:0000313|RefSeq:XP_012554248.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; HAAD01005311; CDG71543.1; -; mRNA.
DR RefSeq; XP_012554248.1; XM_012698794.1.
DR EnsemblMetazoa; XM_012698794.1; XP_012554248.1; GeneID_100199110.
DR EnsemblMetazoa; XM_012698794.2; XP_012554248.1; GeneID_100199110.
DR EnsemblMetazoa; XM_047284482.1; XP_047140438.1; GeneID_100199110.
DR GeneID; 100199110; -.
DR CTD; 100199110; -.
DR OrthoDB; 3039999at2759; -.
DR Proteomes; UP000694840; Unplaced.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd11400; bHLHzip_Myc; 1.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR002418; Tscrpt_reg_Myc.
DR InterPro; IPR012682; Tscrpt_reg_Myc_N.
DR PANTHER; PTHR45851:SF3; MYC PROTEIN; 1.
DR PANTHER; PTHR45851; MYC PROTO-ONCOGENE; 1.
DR Pfam; PF00010; HLH; 1.
DR Pfam; PF01056; Myc_N; 1.
DR PIRSF; PIRSF001705; Myc_protein; 3.
DR PRINTS; PR00044; LEUZIPPRMYC.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000694840}.
FT DOMAIN 244..296
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT COILED 293..327
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 327 AA; 36961 MW; 8D91B2ACA24BFE05 CRC64;
MTGSNWCTHD ILPTDEILLH KSILDTSSPS DDVWKKFLTP PSSPQSIGES SESEETTDSF
DTCARLQYVC DNLDIGLELT TRCTNSFNLG LKLISDCMWS GVLPDLSKIQ SKEKFMCTRK
LTLDAEDLYP SPCPSPLSNM NSSTSVPDCP STSECVDPTA VFPLTSNNEF LFCPTDTDEE
IDVVTIDSKP INIVGLKRQS STSIVYTKIQ TTSVLKRTRS SPAKLRSDRL MRKSALIDDL
DPTSRRASHN VLERKRRIDL KRSFEKLREC VPNLEREEKA PKVVVLKKAL MYILALKTEE
KELTEQKRTL QKENEELNSK LKKILFK
//
