ID   T5A6V6_OPHSC            Unreviewed;       306 AA.
AC   T5A6V6;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Heat-labile enterotoxin, A chain {ECO:0000313|EMBL:EQK97486.1};
GN   ORFNames=OCS_06801 {ECO:0000313|EMBL:EQK97486.1};
OS   Ophiocordyceps sinensis (strain Co18 / CGMCC 3.14243) (Yarsagumba
OS   caterpillar fungus) (Hirsutella sinensis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Ophiocordyceps.
OX   NCBI_TaxID=911162 {ECO:0000313|EMBL:EQK97486.1, ECO:0000313|Proteomes:UP000019374};
RN   [1] {ECO:0000313|EMBL:EQK97486.1, ECO:0000313|Proteomes:UP000019374}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Co18 / CGMCC 3.14243 {ECO:0000313|Proteomes:UP000019374};
RC   TISSUE=Fruit-body {ECO:0000313|EMBL:EQK97486.1};
RX   DOI=10.1007/s11434-013-5929-5;
RA   Hu X., Zhang Y., Xiao G., Zheng P., Xia Y., Zhang X., St Leger R.J.,
RA   Liu X., Wang C.;
RT   "Genome survey uncovers the secrets of sex and lifestyle in caterpillar
RT   fungus.";
RL   Chin. Sci. Bull. 58:2846-2854(2013).
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DR   EMBL; KE659024; EQK97486.1; -; Genomic_DNA.
DR   AlphaFoldDB; T5A6V6; -.
DR   eggNOG; ENOG502T4KB; Eukaryota.
DR   HOGENOM; CLU_086105_0_0_1; -.
DR   Proteomes; UP000019374; Unassembled WGS sequence.
DR   GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.210.10; Heat-Labile Enterotoxin, subunit A; 1.
DR   InterPro; IPR001144; Enterotoxin_A.
DR   Pfam; PF01375; Enterotoxin_a; 1.
DR   PRINTS; PR00771; ENTEROTOXINA.
DR   SUPFAM; SSF56399; ADP-ribosylation; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000019374};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Toxin {ECO:0000256|ARBA:ARBA00022656};
KW   Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..306
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004596674"
FT   REGION          279..306
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        284..306
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   306 AA;  33551 MW;  A9CCC5ECDD9E0322 CRC64;
     MLLKLSLLLP LWASTSISCA APTTPTELLP RSVASQQPQL VHNSPTWLYR GDLRDPEQLK
     AAGGFLPRSR LPSKDTSFGL YNHGEAVGDA GGVRETIYSS TSASFVTAGA YIKTDSLYTS
     SVGGWIYRIR PTPNMIDLEA SLGPGSPFPH DKEFSAMGGI LWEQVDGWIF VTVEKDLDPL
     PPVDAMEIDV TAAEEVFNSL SDRYITNKDY NLEFDRFKAS GGRPELAGFF AAAGKFKNQE
     PWSRYNESTE YYAMRFMEEN GESVGWHGSF PLFGQLDVSA GNVDKEPEPN KGDDGIGKGD
     DKQDGN
//