ID T5AEN2_OPHSC Unreviewed; 666 AA.
AC T5AEN2;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Nucleolar protein 58 {ECO:0000256|ARBA:ARBA00020379};
GN ORFNames=OCS_00363 {ECO:0000313|EMBL:EQL03920.1};
OS Ophiocordyceps sinensis (strain Co18 / CGMCC 3.14243) (Yarsagumba
OS caterpillar fungus) (Hirsutella sinensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Ophiocordyceps.
OX NCBI_TaxID=911162 {ECO:0000313|EMBL:EQL03920.1, ECO:0000313|Proteomes:UP000019374};
RN [1] {ECO:0000313|EMBL:EQL03920.1, ECO:0000313|Proteomes:UP000019374}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Co18 / CGMCC 3.14243 {ECO:0000313|Proteomes:UP000019374};
RC TISSUE=Fruit-body {ECO:0000313|EMBL:EQL03920.1};
RX DOI=10.1007/s11434-013-5929-5;
RA Hu X., Zhang Y., Xiao G., Zheng P., Xia Y., Zhang X., St Leger R.J.,
RA Liu X., Wang C.;
RT "Genome survey uncovers the secrets of sex and lifestyle in caterpillar
RT fungus.";
RL Chin. Sci. Bull. 58:2846-2854(2013).
CC -!- FUNCTION: Required for pre-18S rRNA processing. May bind microtubules.
CC {ECO:0000256|ARBA:ARBA00024837}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the NOP5/NOP56 family.
CC {ECO:0000256|ARBA:ARBA00009211}.
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DR EMBL; KE652187; EQL03920.1; -; Genomic_DNA.
DR AlphaFoldDB; T5AEN2; -.
DR eggNOG; KOG2572; Eukaryota.
DR HOGENOM; CLU_015495_5_0_1; -.
DR Proteomes; UP000019374; Unassembled WGS sequence.
DR GO; GO:0031428; C:box C/D RNP complex; IEA:InterPro.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0032040; C:small-subunit processome; IEA:InterPro.
DR GO; GO:0030515; F:snoRNA binding; IEA:InterPro.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.4070; -; 1.
DR Gene3D; 1.10.246.90; Nop domain; 1.
DR InterPro; IPR045056; Nop56/Nop58.
DR InterPro; IPR012974; NOP58/56_N.
DR InterPro; IPR042239; Nop_C.
DR InterPro; IPR002687; Nop_dom.
DR InterPro; IPR036070; Nop_dom_sf.
DR InterPro; IPR012976; NOSIC.
DR PANTHER; PTHR10894; NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58; 1.
DR PANTHER; PTHR10894:SF1; NUCLEOLAR PROTEIN 58; 1.
DR Pfam; PF01798; Nop; 1.
DR Pfam; PF08156; NOP5NT; 1.
DR SMART; SM00931; NOSIC; 1.
DR SUPFAM; SSF89124; Nop domain; 1.
DR PROSITE; PS51358; NOP; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000019374};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274}.
FT DOMAIN 285..409
FT /note="Nop"
FT /evidence="ECO:0000259|PROSITE:PS51358"
FT REGION 445..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 524..666
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 460..475
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 476..496
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 546..589
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 599..654
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 666 AA; 73684 MW; F3FE468BF70AD824 CRC64;
MSLFVLAETP AGYGLFKAAD KKLFKNDDLA AELGRPEKLV EMLKLKKFVK FDSAAMALEE
AAALKDGKVP TLLTSLLEDL KDEKKASLAV ADIKLGTAIS NLPQFNITPV TGSNTMDIFR
GLREHLPSLI PGLTQENIDR MALGLSHSIS RHKLKFSVNK IDSMIIQAVR LLDDMDKDLN
VFAMRTKEWY GWHFPELAKI LNDNLAYARL VLLAGFRTNI AETDLSEVLP EDTEEAVKKA
AEISMGTEIT EDDLSNIKSL AEQVIRYTEY RAQLSSYLES RMRAIAPNLT VLLGYLIGAR
LIAHSGSLMS LAKAPGSTIQ ILGAEKALFR ALKTKHDTPK YGIIYHSSLI GQASGRNKGK
IARGLASKTA LGLRVDALAN DDEDDEEQRS ILGVSSRIKL ENRLRTLEGR ALLPRVVTVG
PSGEITTPGQ FTLKETRRYN VDADGVGDSA TIEAPNTLNG KKSKDGKKAL IEVVEDQADE
EMGDAKDDAT DDDDEDEKAS TPAKPKLSST EYERLAKLAG LSAKKFKRKY ERGDVQLNAA
GTPKVYSKKE LKKMRKAGEN ETPVKRPETP TKPEPSEKKK KRKAGEIETP VQKLETPSKP
EPSSEKKKKR KAEENETPVK KAESPCKSEP SSEKKKKKRK HVEIEEEAAE TKKDKKQKKK
KRHSEA
//
