ID T5AHY8_OPHSC Unreviewed; 707 AA.
AC T5AHY8;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Glycogen [starch] synthase {ECO:0000256|RuleBase:RU363104};
DE EC=2.4.1.11 {ECO:0000256|RuleBase:RU363104};
GN ORFNames=OCS_02270 {ECO:0000313|EMBL:EQL02021.1};
OS Ophiocordyceps sinensis (strain Co18 / CGMCC 3.14243) (Yarsagumba
OS caterpillar fungus) (Hirsutella sinensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Ophiocordyceps.
OX NCBI_TaxID=911162 {ECO:0000313|EMBL:EQL02021.1, ECO:0000313|Proteomes:UP000019374};
RN [1] {ECO:0000313|EMBL:EQL02021.1, ECO:0000313|Proteomes:UP000019374}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Co18 / CGMCC 3.14243 {ECO:0000313|Proteomes:UP000019374};
RC TISSUE=Fruit-body {ECO:0000313|EMBL:EQL02021.1};
RX DOI=10.1007/s11434-013-5929-5;
RA Hu X., Zhang Y., Xiao G., Zheng P., Xia Y., Zhang X., St Leger R.J.,
RA Liu X., Wang C.;
RT "Genome survey uncovers the secrets of sex and lifestyle in caterpillar
RT fungus.";
RL Chin. Sci. Bull. 58:2846-2854(2013).
CC -!- FUNCTION: Transfers the glycosyl residue from UDP-Glc to the non-
CC reducing end of alpha-1,4-glucan. {ECO:0000256|RuleBase:RU363104}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + H(+) + UDP; Xref=Rhea:RHEA:18549, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:58223, ChEBI:CHEBI:58885; EC=2.4.1.11;
CC Evidence={ECO:0000256|ARBA:ARBA00043769};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:18550;
CC Evidence={ECO:0000256|ARBA:ARBA00043769};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004964, ECO:0000256|RuleBase:RU363104}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 3 family.
CC {ECO:0000256|ARBA:ARBA00010686, ECO:0000256|RuleBase:RU363104}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KE652372; EQL02021.1; -; Genomic_DNA.
DR AlphaFoldDB; T5AHY8; -.
DR eggNOG; KOG3742; Eukaryota.
DR HOGENOM; CLU_015910_1_0_1; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000019374; Unassembled WGS sequence.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd03793; GT3_GSY2-like; 1.
DR Gene3D; 6.10.260.10; -; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR008631; Glycogen_synth.
DR PANTHER; PTHR10176:SF3; GLYCOGEN [STARCH] SYNTHASE; 1.
DR PANTHER; PTHR10176; GLYCOGEN SYNTHASE; 1.
DR Pfam; PF05693; Glycogen_syn; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 2.
PE 3: Inferred from homology;
KW Glycogen biosynthesis {ECO:0000256|ARBA:ARBA00023056,
KW ECO:0000256|RuleBase:RU363104};
KW Glycosyltransferase {ECO:0000256|RuleBase:RU363104};
KW Reference proteome {ECO:0000313|Proteomes:UP000019374};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363104}.
SQ SEQUENCE 707 AA; 80605 MW; 21C986C21E610E17 CRC64;
MASDASRSQT RDVKNHLLFE IATEVAHRVG GIYSVIKSKA PVTTAEYGDR YTLIGPLNRQ
SAAVEVEEMD PPNQEISLTM QSMKERGIDI IYGRWLIEGA PRVLLIDTKT AYGYLDEWKT
DLWNISSIPS PPNDDETNEA IVFGYLVAWF LGEFVSHEKN KAVIAHFHEW LSGVALPLTR
KRRIDVTTIF TTHATLLGRY LCAGSVDFYN NLQYFDVDSE AGKRGIYHRY CIERAAAHSC
DVFTTVSHIT AFESEHLLKR KPDGVLPNGL NVTKFSAVHE FQNLHQQAKE KIHDFVRGHF
YGHYDFEPDN TLYLFTAGRY EFRNKGVDMF IESLARLNHR LKNAGSKMTV VAFIIMPAQT
TSLTVEALKG QAVIKSLRDT THVIEQSIGR RLFERSLKWH DGEPMPDEKE LISGQDRVLL
RRRLFAMKRG GLPPIVTHNM INDHDDPILN QIRRVQLFNH PTDRVKVVFH PEFLNSANPV
LPMDYDDFVR GCHMGVFASY YEPWGYTPAE CTVMGVPSIT TNLSGFGCYM EELIENSSDY
GIYIVDRRTK GVDDSINQLT THMYDFCGKS RRQRINQRNR TERLSDLLDW KRMGMEYVKA
RQLALRRVYA TSFSGAEEEE EDFIPGVEQK ISRPFSVPGS PRDRGGMMTP GDFASLQEGR
EGLNTEDYVA WKLPDEEDPD EYPFPLTLRA KQPVNDSAVV EATLNGN
//
