ID   T5AKQ0_OPHSC            Unreviewed;       534 AA.
AC   T5AKQ0;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Proteinase {ECO:0000313|EMBL:EQL02408.1};
GN   ORFNames=OCS_01880 {ECO:0000313|EMBL:EQL02408.1};
OS   Ophiocordyceps sinensis (strain Co18 / CGMCC 3.14243) (Yarsagumba
OS   caterpillar fungus) (Hirsutella sinensis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Ophiocordyceps.
OX   NCBI_TaxID=911162 {ECO:0000313|EMBL:EQL02408.1, ECO:0000313|Proteomes:UP000019374};
RN   [1] {ECO:0000313|EMBL:EQL02408.1, ECO:0000313|Proteomes:UP000019374}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Co18 / CGMCC 3.14243 {ECO:0000313|Proteomes:UP000019374};
RC   TISSUE=Fruit-body {ECO:0000313|EMBL:EQL02408.1};
RX   DOI=10.1007/s11434-013-5929-5;
RA   Hu X., Zhang Y., Xiao G., Zheng P., Xia Y., Zhang X., St Leger R.J.,
RA   Liu X., Wang C.;
RT   "Genome survey uncovers the secrets of sex and lifestyle in caterpillar
RT   fungus.";
RL   Chin. Sci. Bull. 58:2846-2854(2013).
CC   -!- SIMILARITY: Belongs to the peptidase S33 family.
CC       {ECO:0000256|ARBA:ARBA00010088}.
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DR   EMBL; KE652312; EQL02408.1; -; Genomic_DNA.
DR   AlphaFoldDB; T5AKQ0; -.
DR   eggNOG; ENOG502QXCY; Eukaryota.
DR   HOGENOM; CLU_013364_3_3_1; -.
DR   Proteomes; UP000019374; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR013595; Pept_S33_TAP-like_C.
DR   PANTHER; PTHR43248; 2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE; 1.
DR   PANTHER; PTHR43248:SF29; AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   Pfam; PF08386; Abhydrolase_4; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019374}.
FT   DOMAIN          108..295
FT                   /note="AB hydrolase-1"
FT                   /evidence="ECO:0000259|Pfam:PF00561"
FT   DOMAIN          437..528
FT                   /note="Peptidase S33 tripeptidyl aminopeptidase-like C-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08386"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   534 AA;  59117 MW;  9EBC85114044DB82 CRC64;
     MVMESRSYDS SREKPLAPVS REAARTGQPS LEMLVFCCIL TLAGIATLNR ITVHASHIRW
     TPCPSTYPAS LECGRLAVPV DYNHPNRAQI SLGMVRLRAS TPRALGNLIV NPGGPGNSAV
     SVLARQKQRQ LVSRNLTLHY NIIAPDPRGV GASHPVRCDA DVASRRVPGY ITSIDDFDKL
     ATWSETLGKS CARMTGPVFY HLDTISAARD LDRIRRALGD EKLNYMGVSY GTQLGSQYAE
     LFPEHVGRMV LDGVLDHSQA GIDSLMTESM AAEDSFHRFT RWCNTTSKCA FYSRDLPSIF
     DKLVDMANEK PIPALGCHEG VVKACRPDVT GYELISQAQE DLSYPKEWAR LSRALHEASE
     GNATLLSPRL TPRNESLPVS SQPYTYCYPC ARRARCLAGL RVVARLANLV AHRVRRAGLV
     DDPRQRRHNP ERVLVLEIQI NCIAWPAPVT NPERPLSRER LARAPPILLA NSLHDPSTSV
     VWAVGLREQM PTAVSIFRDG GGHTSYWDYG HVQKAMDAFL LNGTMPEDLA VYRS
//