ID T5CA65_HELPX Unreviewed; 524 AA.
AC T5CA65;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=DNA repair protein RecN {ECO:0000256|ARBA:ARBA00021315, ECO:0000256|PIRNR:PIRNR003128};
DE AltName: Full=Recombination protein N {ECO:0000256|ARBA:ARBA00033408, ECO:0000256|PIRNR:PIRNR003128};
GN ORFNames=N402_01170 {ECO:0000313|EMBL:EQL46646.1};
OS Helicobacter pylori FD423.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1191279 {ECO:0000313|EMBL:EQL46646.1, ECO:0000313|Proteomes:UP000015932};
RN [1] {ECO:0000313|EMBL:EQL46646.1, ECO:0000313|Proteomes:UP000015932}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FD423 {ECO:0000313|EMBL:EQL46646.1,
RC ECO:0000313|Proteomes:UP000015932};
RX PubMed=23012278; DOI=10.1128/JB.01278-12;
RA Gunaletchumy S.P., Teh X., Khosravi Y., Ramli N.S., Chua E.G., Kavitha T.,
RA Mason J.N., Lee H.T., Alias H., Zaidan N.Z., Yassin N.B., Tay L.C.,
RA Rudd S., Mitchell H.M., Kaakoush N.O., Loke M.F., Goh K.L., Vadivelu J.;
RT "Draft genome sequences of Helicobacter pylori isolates from Malaysia,
RT cultured from patients with functional dyspepsia and gastric cancer.";
RL J. Bacteriol. 194:5695-5696(2012).
RN [2] {ECO:0000313|EMBL:EQL46646.1, ECO:0000313|Proteomes:UP000015932}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FD423 {ECO:0000313|EMBL:EQL46646.1,
RC ECO:0000313|Proteomes:UP000015932};
RX PubMed=24051312;
RA Rehvathy V., Tan M.H., Gunaletchumy S.P., Teh X., Wang S., Baybayan P.,
RA Singh S., Ashby M., Kaakoush N.O., Mitchell H.M., Croft L.J., Goh K.L.,
RA Loke M.F., Vadivelu J.;
RT "Multiple genome sequences of Helicobacter pylori strains of diverse
RT disease and antibiotic resistance backgrounds from malaysia.";
RL Genome Announc. 1:E00687-E00713(2013).
CC -!- FUNCTION: May be involved in recombinational repair of damaged DNA.
CC {ECO:0000256|ARBA:ARBA00003618, ECO:0000256|PIRNR:PIRNR003128}.
CC -!- SIMILARITY: Belongs to the RecN family. {ECO:0000256|ARBA:ARBA00009441,
CC ECO:0000256|PIRNR:PIRNR003128}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQL46646.1}.
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DR EMBL; AKHM02000105; EQL46646.1; -; Genomic_DNA.
DR RefSeq; WP_001204453.1; NZ_AKHM02000105.1.
DR AlphaFoldDB; T5CA65; -.
DR PATRIC; fig|1191279.5.peg.217; -.
DR Proteomes; UP000015932; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR004604; DNA_recomb/repair_RecN.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR PANTHER; PTHR11059; DNA REPAIR PROTEIN RECN; 1.
DR PANTHER; PTHR11059:SF0; DNA REPAIR PROTEIN RECN; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF003128; RecN; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|PIRNR:PIRNR003128};
KW DNA repair {ECO:0000256|PIRNR:PIRNR003128}.
FT DOMAIN 28..483
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT COILED 160..221
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 524 AA; 59647 MW; EB9FCF4CA4674FF7 CRC64;
MRDFNNAQIT RLKVRQNAVF EKLDLEFKDG LSAISGASGV GKSVLIASLL GAFGLKESNA
SNIEVELIAP FLDTEEYGIF REDEHEPLVI SVIKKEKTRY FLNQTSLSKN TLKALLKGLI
KRLSNDRFSQ NELNDTLMLS LLDGYIHNEN KAFSPLLGAL EEKFIRLEKL EKERRLLEDK
KRFQKDLEER LNFEKMKLER LDLQEDEYER LLEQKKLLSS KEKLNDKIAL ALEVLENTHK
ITHALESVGH NAEFLKSALL EASALLEKEQ AKLEECERLD IEKVLERLGM LSGIIKDYGS
ITHAKERLGH VKNELYNLKE IDHYCETYHK ETEQLKTECL KLCEEISGFR KEYLAGFNAL
LSAKAKDLLL KSPSLVLEEA PMSEKGAQKL VLNLQNSQLE TLSSGEYSRL RLAFMLLEME
FLKDFKGVLV LDEMDSNLSG EESLAVSKAL ETLSSHSQIF AISHQVHIPA LAKNHILVFK
ENHKSLAKTL NNEERVLEIA RMIGGSENIE SAISFAKEKL KAQE
//
