ID TEG3_EHV1B Reviewed; 317 AA.
AC P28949; Q6S6S4;
DT 01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-1992, sequence version 1.
DT 24-JAN-2024, entry version 64.
DE RecName: Full=Tegument protein UL14 homolog;
GN OrderedLocusNames=48;
OS Equine herpesvirus 1 (strain Ab4p) (EHV-1) (Equine abortion virus).
OC Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC Herpesvirales; Orthoherpesviridae; Alphaherpesvirinae; Varicellovirus;
OC Varicellovirus equidalpha1; Equid alphaherpesvirus 1.
OX NCBI_TaxID=31520;
OH NCBI_TaxID=9796; Equus caballus (Horse).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=1318606; DOI=10.1016/0042-6822(92)90706-u;
RA Telford E.A.R., Watson M.S., McBride K., Davison A.J.;
RT "The DNA sequence of equine herpesvirus-1.";
RL Virology 189:304-316(1992).
CC -!- FUNCTION: Contributes to the nuclear transport of the viral
CC transcriptional activator VP16 during the early phase of infection.
CC Therefore, participates indirectly in the regulation of the immediate-
CC early gene expression. Additionally, seems to be important for
CC efficient nuclear targeting of capsids (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Virion tegument {ECO:0000250}. Host cytoplasm
CC {ECO:0000250}. Host nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the alphaherpesvirinae HHV-1 UL14 protein
CC family. {ECO:0000305}.
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DR EMBL; AY665713; AAT67305.1; -; Genomic_DNA.
DR PIR; C36800; WZBEE1.
DR RefSeq; YP_053093.1; NC_001491.2.
DR SMR; P28949; -.
DR GeneID; 1487539; -.
DR KEGG; vg:1487539; -.
DR Proteomes; UP000001189; Segment.
DR GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR InterPro; IPR005207; Herpes_UL14.
DR Pfam; PF03580; Herpes_UL14; 1.
PE 3: Inferred from homology;
KW Host cytoplasm; Host nucleus; Reference proteome; Virion; Virion tegument.
FT CHAIN 1..317
FT /note="Tegument protein UL14 homolog"
FT /id="PRO_0000115936"
FT REGION 166..291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 198..216
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..238
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..268
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 317 AA; 35816 MW; CCBF7BDCB87BF9E5 CRC64;
MSFSARSRRQ RLQLEEAYQR EMIFKMHTLD LVREGVNKRS PAFVRAFTSA KEASLDLDRY
MQAHSRVGRV EQNARALAQR VEAQAAVGEI LDRHRRFLHP DFIDNFDSRE DSIVEREERL
GDVLSDINCD GGGGEVGDPQ EWLGHEDEAL LMRWMLEEAP RVSTRIAADP HSPRSTCPAP
RKAPEDARCG ARKPGEVNNY TPSAQPRSQE TTVDHLASPD EGTRLGDRTR DLEHHSTAPM
RTHPNVLASE RRRLGVVHQR EKSSESQESA TRSKAIVGQE DQKWLGGIPP LSDEELQVDM
GIPTMNGPIY PDYHRTA
//
